Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 11/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17393564 | 0.88 | KCNH2 (0.48) | IDO1MAP4K4KCNH2MINK1PIK3CA | |
| SCHEMBL22211534 | 0.74 | IDO1 (0.42) | IDO1MAP4K4DYRK3CCNA2CDK2 | |
| SCHEMBL7085072 | 0.73 | KCNH2 (0.50) | MAP4K4KCNH2MINK1PIK3CAPI4KB | |
| SCHEMBL14907071 | 0.72 | TSHR (0.56) | IDO1DYRK3CCNA2CDK2CDK5 | |
| SCHEMBL15674548 | 0.72 | IDO1 (0.46) | IDO1MAP4K4KCNH2MINK1PIK3CA | |
| SCHEMBL17393018 | 0.72 | KCNH2 (0.49) | MAP4K4KCNH2MINK1PIK3CAPI4KB | |
| SCHEMBL16068081 | 0.71 | IDO1 (0.44) | IDO1MAP4K4KCNH2MINK1DYRK3 | |
| SCHEMBL1577931 | 0.70 | TSHR (0.54) | IDO1MAP4K4KCNH2MINK1CYP1A2 | |
| SCHEMBL2547240 | 0.68 | TSHR (0.46) | IDO1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL23354192 | 0.68 | P2RX7 (0.47) | MAP4K4KCNH2MINK1PIK3CAPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975030-B1 | DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2020-07-15 | — | — | EP | disclosed |