Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16068268 | 0.88 | CA2 (0.46) | IDO1ALDH1A1KDM4EHSD17B10KMO | |
| SCHEMBL22211420 | 0.83 | MPL (0.37) | ALDH1A1KDM4EHSD17B10CA2CHKA | |
| SCHEMBL22211794 | 0.83 | IDO1 (0.42) | IDO1KDM4ECA2CHKAPIM3 | |
| SCHEMBL18700477 | 0.77 | IDO1 (0.47) | IDO1ALDH1A1HSD17B10KMODYRK3 | |
| SCHEMBL39774 | 0.77 | IDO1 (0.50) | IDO1ALDH1A1KMODYRK3CCNA2 | |
| SCHEMBL22211510 | 0.74 | IDO1 (0.42) | IDO1ALDH1A1KDM4EHSD17B10DYRK3 | |
| SCHEMBL17392797 | 0.72 | CA2 (0.47) | ALDH1A1KDM4EHSD17B10CA2CHKA | |
| SCHEMBL16971331 | 0.71 | IDO1 (0.44) | IDO1ALDH1A1KDM4EDYRK3CCNA2 | |
| SCHEMBL16068058 | 0.71 | CA2 (0.46) | IDO1ALDH1A1KDM4EHSD17B10KMO | |
| SCHEMBL16068170 | 0.71 | AGPAT2 (0.44) | IDO1ALDH1A1KDM4EHSD17B10KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975030-B1 | DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2020-07-15 | — | — | EP | disclosed |