Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | APP | P05067 | 6/20 | 0.64 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221190 | 1.00 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPGSK3B | |
| Cetostearyl Alcohol SCHEMBL27567712 | 0.95 | LMNA (0.62) | LMNASMN1; SMN2TDP1APPGSK3B | |
| SCHEMBL28067645 | 0.94 | LMNA (0.75) | LMNASMN1; SMN2TDP1APPGSK3B | |
| SCHEMBL10482589 | 0.90 | APP (0.76) | LMNASMN1; SMN2TDP1APPESR1 | |
| Alcohol SCHEMBL27701847 | 0.89 | LMNA (0.65) | LMNASMN1; SMN2TDP1APPGSK3B | |
| SCHEMBL2489079 | 0.89 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPGSK3B | |
| SCHEMBL59457 | 0.89 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPGSK3B | |
| SCHEMBL30746 | 0.89 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPGSK3B | |
| SCHEMBL8872231 | 0.89 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPGSK3B | |
| SCHEMBL4070148 | 0.89 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362151-B2 | Hybrid polymer materials for liquid crystal alignment layers | ELSICON, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| EP-2513157-A1 | HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS | Li, Chunhong (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011084546-A1 | HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS | LI CHUNHONG (US) | 2011-07-14 | — | — | WO | disclosed |
| US-20100305230-A1 | HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS | ELSICON, INC. (US) | 2010-12-02 | — | — | US | disclosed |