SCHEMBL22212604

SCHEMBL22212604

Cn1ccc2c(Cc3ccc(-c4ccc(F)nc4)nc3)cc(C(=O)NC3CCCCC3)nc21

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 6/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22212633 0.94 CHRM1 (0.62) CHRM1
SCHEMBL19932636 0.91 CHRM1 (0.68) CHRM1
SCHEMBL21545764 0.90 CHRM1 (0.77) CHRM1
SCHEMBL19932634 0.88 CHRM1 (0.85) CHRM1
SCHEMBL19932643 0.85 CHRM1 (0.64) CHRM1
SCHEMBL22212603 0.85 CHRM1 (0.63) CHRM1
SCHEMBL6891544 0.84 CHRM1 (0.47) CHRM1
SCHEMBL22212602 0.84 CHRM1 (0.62) CHRM1
SCHEMBL22212610 0.84 CHRM1 (0.63) CHRM1
SCHEMBL21545798 0.84 CHRM1 (0.77) CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507289-B1 MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS SUVEN LIFE SCIENCES LTD (IN) 2020-07-15 EP disclosed