SCHEMBL22220069

SCHEMBL22220069

C=C(C)C(=O)OCCOCc1cc(-c2ccc(C(=O)c3ccc(-c4ccc(OC)c(COCCOC(=O)C(=C)C)c4)cc3)cc2)ccc1OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
TSHR P16473 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ALDH1A1 P00352 6/20 0.37
GAA P10253 2/20 0.37
PDE4A P27815 2/20 0.37
PDE4B Q07343 2/20 0.37
PDE4C Q08493 2/20 0.37
PDE4D Q08499 2/20 0.37
POLB P06746 2/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ADRB2 P07550 1/20 0.37
ALOX5 P09917 1/20 0.36
MAPK1 P28482 1/20 0.36
MAPK10 P53779 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24117483 0.95 ELANE (0.42) TSHRCYP1A2CYP2C19ALDH1A1PDE4A
SCHEMBL24115974 0.93 ALDH1A1 (0.42) THRBTSHRALDH1A1GAAPOLB
SCHEMBL24117426 0.89 HTT (0.44) TSHRCYP1A2CYP2C19PDE4APDE4B
SCHEMBL812217 0.87 ALDH1A1 (0.39) THRBTSHRALDH1A1GAAPOLB
SCHEMBL21889105 0.85 TSHR (0.35) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL21889385 0.85 KMT2A (0.36) THRBTSHRCYP1A2CYP3A4CYP2C9
SCHEMBL822715 0.82 ALDH1A1 (0.36) THRBTSHRALDH1A1GAAPOLB
SCHEMBL22220070 0.82 CYP1A2 (0.44) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL24117460 0.81 ELANE (0.41) TSHRCYP1A2CYP2C19ALDH1A1PDE4A
SCHEMBL24756135 0.81 GAA (0.40) TSHRALDH1A1GAAPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220403066-A1 CURED PRODUCT, OPTICAL ELEMENT, OPTICAL APPARATUS, AND IMAGE PICKUP APPARATUS CANON KABUSHIKI KAISHA (JP) 2022-12-22 US disclosed
US-20200223781-A1 COMPOUND, RESIN PRECURSOR, CURED PRODUCT, OPTICAL ELEMENT, OPTICAL SYSTEM, INTERCHANGEABLE LENS FOR CAMERA, OPTICAL DEVICE, CEMENTED LENS, AND PRODUCTION METHOD FOR CEMENTED LENS NIKON CORPORATION (JP) 2020-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200223781-A1 COMPOUND, RESIN PRECURSOR, CURED PRODUCT, OPTICAL ELEMENT, OPTICAL SYSTEM, INTERCHANGEABLE LENS FOR CAMERA, OPTICAL DEVICE, CEMENTED LENS, AND PRODUCTION METHOD FOR CEMENTED LENS RAD51, CDH1, RCC2 THRB 3983/4885TSHR 3526/4885CYP1A2 2107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.