Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 6/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29588691 | 0.78 | CSNK1A1 (0.40) | CSNK1A1CLK4KDM4ENPC1RAB9A | |
| SCHEMBL5030532 | 0.78 | CSNK1A1 (0.40) | CSNK1A1CLK4KDM4ENPC1RAB9A | |
| SCHEMBL31409720 | 0.77 | KDM4E (0.40) | CSNK1A1CLK4KDM4ENPC1RAB9A | |
| SCHEMBL22208091 | 0.77 | CSNK1A1 (0.47) | CSNK1A1CLK4KDM4ENPC1RAB9A | |
| SCHEMBL30248919 | 0.77 | CSNK1A1 (0.47) | CSNK1A1CLK4KDM4ENPC1RAB9A | |
| SCHEMBL11309729 | 0.74 | CSNK1A1 (0.40) | CSNK1A1CLK4KDM4ENPC1RAB9A | |
| SCHEMBL13257627 | 0.74 | SRC (0.40) | KDM4E | |
| SCHEMBL26324937 | 0.72 | KDM5A (0.43) | CSNK1A1CLK4KDM4EKMT2AALDH1A1 | |
| SCHEMBL5482012 | 0.70 | KDM4E (0.58) | KDM4ENPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL19009020 | 0.69 | TSHR (0.39) | CSNK1A1CLK4KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146613-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2020-07-16 | — | — | WO | disclosed |