Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MBOAT4 | Q96T53 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18299745 | 0.80 | TSHR (0.35) | KDM4EKDRABL1CSNK1A1CLK4 | |
| SCHEMBL30971161 | 0.80 | HTT (0.46) | KDM4EKDRABL1CSNK1A1CLK4 | |
| SCHEMBL5030532 | 0.78 | CSNK1A1 (0.40) | KDM4EKDRABL1CSNK1A1CLK4 | |
| SCHEMBL29588691 | 0.78 | CSNK1A1 (0.40) | KDM4EKDRABL1CSNK1A1CLK4 | |
| SCHEMBL1145686 | 0.77 | CSNK1A1 (0.39) | KDM4EKDRABL1CSNK1A1CLK4 | |
| SCHEMBL22220100 | 0.77 | CSNK1A1 (0.39) | KDM4EKDRABL1CSNK1A1CLK4 | |
| SCHEMBL11309729 | 0.74 | CSNK1A1 (0.40) | KDM4EKDRABL1CSNK1A1CLK4 | |
| SCHEMBL20489454 | 0.74 | HTT (0.44) | KDM4EKDRABL1CSNK1A1CLK4 | |
| SCHEMBL5482012 | 0.74 | KDM4E (0.58) | KDM4EKDRNPSR1ALDH1A1KMT2A | |
| SCHEMBL20698729 | 0.73 | LMNA (0.34) | KDM4ENPSR1KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |