SCHEMBL222203

SCHEMBL222203

CCOC(=O)c1cnc(N)s1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.58
CDC7 O00311 4/20 0.57
DBF4 Q9UBU7 4/20 0.57
ALDH1A1 P00352 6/20 0.49
CYP1A2 P05177 2/20 0.49
MAPT P10636 2/20 0.49
HPGD P15428 2/20 0.49
GAA P10253 2/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
FHIT P49789 1/20 0.45
HSD17B10 Q99714 1/20 0.44
MAPK1 P28482 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7091737 0.98 SMN1; SMN2 (0.56) SMN1; SMN2CDC7DBF4ALDH1A1CYP1A2
SCHEMBL2648928 0.83 SMN1; SMN2 (0.55) SMN1; SMN2CDC7DBF4ALDH1A1CYP1A2
SCHEMBL24753892 0.83 SMN1; SMN2 (0.43) SMN1; SMN2CDC7DBF4ALDH1A1CYP1A2
SCHEMBL286068 0.82 CDC7 (0.60) SMN1; SMN2CDC7DBF4ALDH1A1CYP1A2
SCHEMBL16933028 0.82 CDC7 (0.60) SMN1; SMN2CDC7DBF4ALDH1A1CYP1A2
SCHEMBL13593795 0.81 SMN1; SMN2 (0.60) SMN1; SMN2CDC7DBF4ALDH1A1CYP1A2
SCHEMBL6476591 0.81 CDC7 (0.59) SMN1; SMN2CDC7DBF4ALDH1A1CYP1A2
SCHEMBL274346 0.81 CDC7 (0.59) SMN1; SMN2CDC7DBF4ALDH1A1CYP1A2
SCHEMBL33099 0.80 KDM4E (0.43) SMN1; SMN2ALDH1A1MAPTHPGDGAA
SCHEMBL5911684 0.80 CDC7 (0.55) SMN1; SMN2CDC7DBF4ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 726 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024615-A Preparation method and application of algal polysaccharide derivative 马强 2023-11-10 CN claimed
CN-101265275-B Diethyl 4-{6-[5-(2-chloro-6-methylanilinoformacyl)-thiazolyl-2-amino]-2-methylpyrimidin-4}-piperazin-1-phosphate INST MATERIA MEDICA CAMS 2012-09-05 CN claimed
WO-2011104540-A1 ONE STEP PROCESS FOR THE PREPARATION OF CAPECITABINE GENERICS [UK] LIMITED (GB) 2011-09-01 WO claimed
CN-101323629-B 4-{6-[5-(2-chlorinde-6- methylaniline formyl)-thiazole-2-amido]-2-methyl pyrimidine-4}-piperazine-1- diethyl methylphosphate JIANGSU CHIA TAI TIANQING PHAR 2011-08-17 CN claimed
CN-101323629-A 4-{6-[5-(2-chlorinde-6- methylaniline formyl)-thiazole-2-amido]-2-methyl pyrimidine-4}-piperazine-1- diethyl methylphosphate INST MATERIA MEDICA CAMS (CN) 2008-12-17 CN claimed
CN-101265275-A Diethyl 4-{6-[5-(2-chloro-6-methylanilinoformacyl)-thiazolyl-2-amino]-2-methylpyrimidin-4}-piperazin-1-phosphate INST MATERIA MEDICA CAMS (CN) 2008-09-17 CN claimed
EP-3901151-B1 HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2026-04-01 EP disclosed
US-12528810-B2 Small molecule inhibitors of DYRK/CLK and uses thereof ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-01-20 US disclosed
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-12-25 US disclosed
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 EP disclosed
US-20250340886-A1 INTRACELLULAR KINASE ASSOCIATED WITH RESISTANCE AGAINST ANTI-TUMOUR IMMUNE RESPONSES, AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2025-11-06 US disclosed
US-12435061-B2 Compounds and compositions for use in treating skin disorders KAMARI PHARMA LTD. (IL) 2025-10-07 US disclosed
US-20250296928-A1 A SYNTHESIS SCHEME AND PROCEDURES FOR PREPARING A SIK3 INHIBITOR AND INTERMEDIATES THEREOF IOMX THERAPEUTICS AG (DE) 2025-09-25 US disclosed
EP-0540143-A2 Compounds and methods for inhibition of HIV and related viruses Medivir Aktiebolag (SE) 1993-05-05 EP disclosed
WO-1993003022-A1 COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES MEDIVIR AB (SE) 1993-02-18 WO disclosed
US-5120752-A N-(1-(20(3-pyridyloxy)phenyl)cyclopropyl) alkyl-N-hydroxyurea compounds, antiinflammatory agents ABBOTT LABORATORIES (US) 1992-06-09 US disclosed
EP-0436199-A1 Cyclopropyl derivative lipoxygenase inhibitors ABBOTT LABORATORIES (US) 1991-07-10 EP disclosed
US-4324899-A 2-Amino-5-cyanothiazoles and their preparation EASTMAN KODAK COMPANY (US) 1982-04-13 US disclosed
US-4160764-A AZO ATTACHED TO AMINO AND ALKOXY SUBSTITUTED PHENYL, DYEING AND PRINTING CELLULOSE ACETATES, POLYAMIDES, POLYURETHANES, POLYOLEFINS, POLYCARBONATES, POLYESTERS HOECHST AKTIENGESELLSCHAFT (DE) 1979-07-10 US disclosed
US-4056523-A SULFONAMIDO SUBSTITUTED HOECHST AKTIENGESELLSCHAFT (DT) 1977-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435061-B2 Compounds and compositions for use in treating skin disorders RDX, HAX1, F12 SMN1; SMN2 3452/4885CDC7 4337/4885DBF4 4624/4885
US-12528810-B2 Small molecule inhibitors of DYRK/CLK and uses thereof CLK3, CLK2, CLK1 SMN1; SMN2 3372/4885CDC7 247/4885DBF4 708/4885
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR CRBN, CUL1, CBL SMN1; SMN2 566/4885CDC7 2635/4885DBF4 3113/4885
US-20250296928-A1 A SYNTHESIS SCHEME AND PROCEDURES FOR PREPARING A SIK3 INHIBITOR AND INTERMEDIATES THEREOF SIK3, SIK1, SIK2 SMN1; SMN2 3631/4885CDC7 245/4885DBF4 2740/4885
US-20250340886-A1 INTRACELLULAR KINASE ASSOCIATED WITH RESISTANCE AGAINST ANTI-TUMOUR IMMUNE RESPONSES, AND USES THEREOF SIK3, SIK1, SIK2 SMN1; SMN2 3539/4885CDC7 248/4885DBF4 2400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.