Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.55 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | FHIT | P49789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912617 | 0.87 | CDC7 (0.57) | CDC7DBF4ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL3843901 | 0.85 | CDC7 (0.56) | CDC7DBF4ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1646493 | 0.84 | CDC7 (0.55) | CDC7DBF4ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL4989265 | 0.84 | CDC7 (0.55) | CDC7DBF4ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9939468 | 0.84 | CDC7 (0.55) | CDC7DBF4ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL5492565 | 0.83 | LOXL2 (0.41) | CDC7DBF4ALDH1A1GAAHPGD | |
| SCHEMBL15896622 | 0.83 | CDC7 (0.54) | CDC7DBF4ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL11705050 | 0.83 | CDC7 (0.54) | CDC7DBF4ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL3162147 | 0.81 | CDC7 (0.52) | CDC7DBF4ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL28267334 | 0.81 | CDC7 (0.52) | CDC7DBF4ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848546-B | 2- (aminomethyl) thiazole-5-nitrile and synthesis method thereof | 南通大学 | 2022-08-12 | — | — | CN | claimed |
| CN-111848546-A | 2- (aminomethyl) thiazole-5-nitrile and synthesis method thereof | 南通大学 | 2020-10-30 | — | — | CN | claimed |
| CN-113943263-B | Synthesis method of 2- (aminomethyl) -1, 3-thiazole-5-carboxylic acid methyl ester | 凯美克(上海)医药科技有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-111848546-B | 2- (aminomethyl) thiazole-5-nitrile and synthesis method thereof | 南通大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-111848546-A | 2- (aminomethyl) thiazole-5-nitrile and synthesis method thereof | 南通大学 | 2020-10-30 | — | — | CN | disclosed |
| US-20060287374-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287374-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | HSD11B1, HSD17B1, HSD11B2 | CDC7 2448/4885DBF4 4486/4885ALDH1A1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.