⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764839 | 0.80 | ELANE (0.46) | — | |
| SCHEMBL12230935 | 0.79 | — | — | |
| SCHEMBL385083 | 0.78 | ALDH1A1 (0.39) | — | |
| SCHEMBL5422387 | 0.78 | CYP4F2 (0.34) | — | |
| SCHEMBL9688367 | 0.77 | — | — | |
| SCHEMBL9687076 | 0.77 | — | — | |
| SCHEMBL9235035 | 0.77 | — | — | |
| SCHEMBL47401 | 0.76 | — | — | |
| SCHEMBL6247891 | 0.76 | — | — | |
| SCHEMBL4400197 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046153-A1 | PRODRUG ESTERS OF CEFTRIAXONE | RANBAXY LABORATORIES LIMITED (IN) | 2004-06-03 | — | — | WO | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| EP-0370454-B1 | Renin-inhibiting amino diol derivatives | HOECHST AG (DE) | 1994-04-20 | — | — | EP | claimed |
| US-5194634-A | Coenzyme A inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1993-03-16 | — | — | US | claimed |
| US-5157134-A | HMG-COA reductase inhibitors; antilipemic agents; promotes high-density lipoproteins; antitumor agents | E. R. SQUIBB & SONS, INC. (US) | 1992-10-20 | — | — | US | claimed |
| EP-0370454-A2 | Renin-inhibiting amino diol derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | claimed |
| EP-0329013-A2 | Renin-inhibiting amino acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | claimed |
| WO-2011084846-A1 | QUATERNARY AMMONIUM SALT PRODRUGS | ALKERMES, INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2004046153-A1 | PRODRUG ESTERS OF CEFTRIAXONE | RANBAXY LABORATORIES LIMITED (IN) | 2004-06-03 | — | — | WO | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | disclosed |
| EP-0497978-B1 | CEPHALOSPORIN COMPOUNDS AND PRODUCTION THEREOF | KYOTO PHARMA IND (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-4847286-A | ANTIALLERGENS | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0293771-A2 | Cephalosporin compound and pharmaceutical composition thereof | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1988-12-07 | — | — | EP | disclosed |
| EP-0108942-B1 | CEPHALOSPORIN DERIVATIVES, METHODS OF PRODUCTION THEREOF AND PROPHYLACTIC AND THERAPEUTIC AGENTS FOR BACTERIAL INFECTION | KYOTO PHARMA IND (JP) | 1988-03-02 | — | — | EP | disclosed |
| EP-0233946-A1 | CHROMOGLYCIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1987-09-02 | — | — | EP | disclosed |
| US-4605651-A | BACTERICIDES | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1986-08-12 | — | — | US | disclosed |
| EP-0108942-A2 | Cephalosporin derivatives, methods of production thereof and prophylactic and therapeutic agents for bacterial infection | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1984-05-23 | — | — | EP | disclosed |