⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116575 | 0.77 | — | — | |
| SCHEMBL12230935 | 0.77 | — | — | |
| SCHEMBL2222032 | 0.77 | — | — | |
| SCHEMBL9687076 | 0.75 | — | — | |
| SCHEMBL9688367 | 0.75 | — | — | |
| SCHEMBL10004131 | 0.75 | DGAT1 (0.44) | — | |
| SCHEMBL5764839 | 0.73 | ELANE (0.46) | — | |
| SCHEMBL399728 | 0.73 | CYP4F2 (0.52) | — | |
| SCHEMBL28136788 | 0.70 | — | — | |
| SCHEMBL7826296 | 0.69 | TRPA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633247-A1 | 2-Bromo- and 2-nitroxy derivatives of 3-bromo- and 3,3-dibromo-4-oxo-azetidines, processes for the preparation thereof and use thereof | PLIVA FARMACEUTSKA KEMIJSKA PREHRAMBENA I KOZMETICKA INDUSTRIJA DIONICKO DRUSTVO ZAGREB (HR) | 1995-01-11 | — | — | EP | disclosed |