Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Oxide SCHEMBL725619 | 1.00 | ELANE (0.58) | ELANEKMT2AATMGAAALDH1A1 | |
| Methacrylic Acid SCHEMBL21314881 | 0.97 | ELANE (0.55) | ELANEKMT2AATMGAAALDH1A1 | |
| SCHEMBL87437 | 0.86 | ELANE (0.73) | ELANEKMT2AATMGAAALDH1A1 | |
| Benzene SCHEMBL27862765 | 0.86 | ELANE (0.73) | ELANEKMT2AATMGAAALDH1A1 | |
| Benzene SCHEMBL28301757 | 0.86 | ELANE (0.73) | ELANEKMT2AATMGAAALDH1A1 | |
| SCHEMBL15058 | 0.86 | ELANE (0.73) | ELANEKMT2AATMGAAALDH1A1 | |
| Glycidol SCHEMBL27968005 | 0.85 | ELANE (0.52) | ELANEKMT2AATMGAAALDH1A1 | |
| Oxirane SCHEMBL9705928 | 0.85 | ELANE (0.63) | ELANEKMT2AATMGAAALDH1A1 | |
| Water SCHEMBL11049169 | 0.84 | ELANE (0.71) | ELANEKMT2AATMGAAALDH1A1 | |
| Methyl Alcohol SCHEMBL29034962 | 0.84 | ELANE (0.71) | ELANEKMT2AATMGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114306094-B | Dental restoration resin composition and preparation method and application thereof | 山东大学 | 2022-11-22 | — | — | CN | claimed |
| US-10960103-B2 | Bone cement composition and kit thereof | DRAGON CROWN MEDICAL CO., LTD. (CN) | 2021-03-30 | — | — | US | claimed |
| US-10905793-B2 | Bone cement composition kit | DRAGON CROWN MEDICAL CO., LTD. (CN) | 2021-02-02 | — | — | US | claimed |
| US-20190201575-A1 | BONE CEMENT COMPOSITION AND KIT THEREOF | DRAGON CROWN MEDICAL CO., LTD. (CN) | 2019-07-04 | — | — | US | claimed |
| US-20190076570-A1 | BONE CEMENT COMPOSITION KIT | DRAGON CROWN MEDICAL CO., LTD. (CN) | 2019-03-14 | — | — | US | claimed |
| US-20190030207-A1 | BONE CEMENT COMPOSITION AND KIT THEREOF | DRAGON CROWN MEDICAL CO., LTD. (CN) | 2019-01-31 | — | — | US | claimed |
| WO-2011126647-A2 | POLYMERIZABLE ISOCYANURATE MONOMERS AND DENTAL COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-10-13 | — | — | WO | claimed |
| US-7888400-B2 | comprises a cyclic allylic sulfide moiety attached to a (meth)acryloyl moiety and photoinitiators, having shrinkage inhibition, compressive and tensile strength, used in dentistry as crowns, fillers, adhesives, seals, inserts, laminate veneers or cements | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-02-15 | — | — | US | claimed |
| US-7780449-B2 | Hydrophilic endodontic sealing compositions and methods for using such compositions | ULTRADENT PRODUCTS, INC. (US) | 2010-08-24 | — | — | US | claimed |
| US-7320598-B2 | Method for filling and sealing a root canal | ULTRADENT PRODUCTS, INC. (US) | 2008-01-22 | — | — | US | claimed |
| US-6652282-B2 | Endodontic sealing compositions and methods for using such compositions | ULTRADENT PRODUCTS, INC. | 2003-11-25 | — | — | US | claimed |
| US-20030199605-A1 | Hydrophilic endodontic sealing compositions and methods for using such compositions | ULTRADENT PRODUCTS, INC. | 2003-10-23 | — | — | US | claimed |
| US-20030194682-A1 | Method for filling and sealing a root canal | JENSEN STEVEN D (US) | 2003-10-16 | — | — | US | claimed |
| US-6500004-B2 | FOR SEALING A ROOT CANAL; INCLUDE RESINS THAT PROMOTE ADHESION TO HYDROPHILIC DENTAL TISSUES SUCH AS ALKYL METHACRYLATES AND DERIVATIVES THEREOF, SUCH AS OXYPHOSPHORO METHACRYLATES | ULTRADENT PRODUCTS, INC. | 2002-12-31 | — | — | US | claimed |
| US-20020177100-A1 | Endodontic sealing compositions and methods for using such compositions | JENSEN STEVEN D (US) | 2002-11-28 | — | — | US | claimed |
| US-20020123024-A1 | Endodontic sealing compositions and methods for using such compositions | ULTRADENT PRODUCTS, INC. | 2002-09-05 | — | — | US | claimed |
| WO-2002047572-A1 | ENDODONTIC SEALING COMPOSITIONS AND METHODS FOR USING SUCH COMPOSITIONS | ULTRADENT PRODUCTS, INC. (US) | 2002-06-20 | — | — | WO | claimed |
| US-6071528-A | CURABLE PHOSPHATE OR PHOSPHONATE ESTER OF (POLY)HYDROXYALKYL METHACRYLATE MONOMER; BONDING AND TENSILE STRENGTH; | ULTRADENT PRODUCTS, INC. (US) | 2000-06-06 | — | — | US | claimed |
| EP-0556118-B1 | Process for including substances of liquid to solid consistency in (meth)acrylic resins | ATOCHEM ELF SA (FR) | 1997-04-16 | — | — | EP | claimed |
| US-5362771-A | Process for inclusion in (meth)acrylic resins of substances of liquid to solid consistency | ELF ATOCHEM, S.A. (FR) | 1994-11-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199605-A1 | Hydrophilic endodontic sealing compositions and methods for using such compositions | HLCS, NLRP3, ATP5PO | ELANE 4631/4885KMT2A 4559/4885ATM 2202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.