Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224105 | 0.95 | MAPT (0.43) | MAPTL3MBTL1KDM4EPOLBNPSR1 | |
| SCHEMBL2222576 | 0.89 | MAPT (0.44) | MAPTL3MBTL1KDM4EPOLBNPSR1 | |
| SCHEMBL12517306 | 0.84 | MAPT (0.52) | MAPTL3MBTL1KDM4EPOLBNPSR1 | |
| SCHEMBL2224108 | 0.84 | L3MBTL1 (0.44) | MAPTL3MBTL1KDM4EPOLBNPSR1 | |
| SCHEMBL14650600 | 0.84 | MAPT (0.44) | MAPTL3MBTL1KDM4EPOLBNPSR1 | |
| SCHEMBL2225299 | 0.83 | MAPT (0.42) | MAPTL3MBTL1KDM4EPOLBNPSR1 | |
| SCHEMBL2225036 | 0.83 | MAPT (0.50) | MAPTL3MBTL1KDM4EPOLBNPSR1 | |
| SCHEMBL2224662 | 0.81 | MAPT (0.52) | MAPTL3MBTL1KDM4EPOLBNPSR1 | |
| SCHEMBL2222833 | 0.80 | MAPT (0.47) | MAPTL3MBTL1KDM4EPOLBNPSR1 | |
| SCHEMBL2222782 | 0.80 | MAPT (0.51) | MAPTL3MBTL1KDM4EPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088201-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-07-21 | — | — | WO | claimed |
| WO-2011088201-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-07-21 | — | — | WO | disclosed |