SCHEMBL22227765

SCHEMBL22227765

c1ccc(-c2ccc(-c3cc(-c4cccnc4)nc(-c4ccc(-c5cc6ccccc6c6ccccc56)cc4)n3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 7/20 0.67
CYP19A1 P11511 2/20 0.54
DHODH Q02127 1/20 0.52
GPR84 Q9NQS5 1/20 0.49
CYP11B2 P19099 6/20 0.47
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
NTSR1 P30989 1/20 0.44
CYP2C9 P11712 3/20 0.44
GLA P06280 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
TSHR P16473 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
CYP17A1 P05093 1/20 0.43
HIPK2 Q9H2X6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17807971 0.97 CYP11B1 (0.67) CYP11B1CYP19A1DHODHGPR84CYP11B2
SCHEMBL30296752 0.97 CYP11B1 (0.67) CYP11B1CYP19A1DHODHGPR84CYP11B2
SCHEMBL17918051 0.97 CYP11B1 (0.67) CYP11B1CYP19A1DHODHGPR84CYP11B2
SCHEMBL19650642 0.97 CYP11B1 (0.67) CYP11B1CYP19A1DHODHGPR84CYP11B2
SCHEMBL24252242 0.96 CYP11B1 (0.68) CYP11B1CYP19A1DHODHGPR84CYP11B2
SCHEMBL17918052 0.96 CYP11B1 (0.68) CYP11B1CYP19A1DHODHGPR84CYP11B2
SCHEMBL30857455 0.96 CYP11B1 (0.68) CYP11B1CYP19A1DHODHGPR84CYP11B2
SCHEMBL24252593 0.96 CYP11B1 (0.68) CYP11B1CYP19A1DHODHGPR84CYP11B2
SCHEMBL24252590 0.94 CYP11B1 (0.62) CYP11B1CYP19A1DHODHGPR84CYP11B2
SCHEMBL19762057 0.94 CYP11B1 (0.65) CYP11B1CYP19A1DHODHGPR84CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3683212-B1 COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2025-11-05 EP disclosed
US-12221430-B2 Compound having pyrimidine ring structure and organic electroluminescence device HODOGAYA CHEMICAL CO., LTD. (JP) 2025-02-11 US disclosed
US-20200277272-A1 COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2020-09-03 US disclosed
US-20200277272-A1 COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2020-09-03 US disclosed
EP-3683212-A1 COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2020-07-22 EP disclosed
CN-111094264-A Compound having pyrimidine ring structure and organic electroluminescent element 保土谷化学工业株式会社 2020-05-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200277272-A1 COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE SLC29A1, ADORA1, SLC29A2 CYP11B1 2487/4885CYP19A1 1296/4885DHODH 986/4885
US-12221430-B2 Compound having pyrimidine ring structure and organic electroluminescence device SLC29A1, SLC29A2, ADORA1 CYP11B1 2463/4885CYP19A1 1130/4885DHODH 773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.