SCHEMBL17807971

SCHEMBL17807971

c1ccc(-c2ccc(-c3cc(-c4ccc(-c5cccnc5)cc4)nc(-c4ccc(-c5cc6ccccc6c6ccccc56)cc4)n3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 4/20 0.67
DHODH Q02127 1/20 0.52
CYP19A1 P11511 2/20 0.50
CYP11B2 P19099 3/20 0.47
CYP17A1 P05093 1/20 0.47
GPR84 Q9NQS5 1/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 3/20 0.44
HPGD P15428 2/20 0.44
NTSR1 P30989 1/20 0.44
GLA P06280 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C9 P11712 2/20 0.44
CLK4 Q9HAZ1 2/20 0.44
TSHR P16473 1/20 0.44
CYP2A6 P11509 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19650642 1.00 CYP11B1 (0.67) CYP11B1DHODHCYP19A1CYP11B2CYP17A1
SCHEMBL17918051 1.00 CYP11B1 (0.67) CYP11B1DHODHCYP19A1CYP11B2CYP17A1
SCHEMBL30296752 1.00 CYP11B1 (0.67) CYP11B1DHODHCYP19A1CYP11B2CYP17A1
SCHEMBL17918052 0.99 CYP11B1 (0.68) CYP11B1DHODHCYP19A1CYP11B2CYP17A1
SCHEMBL30857455 0.99 CYP11B1 (0.68) CYP11B1DHODHCYP19A1CYP11B2CYP17A1
SCHEMBL24252593 0.99 CYP11B1 (0.68) CYP11B1DHODHCYP19A1CYP11B2CYP17A1
SCHEMBL24252242 0.99 CYP11B1 (0.68) CYP11B1DHODHCYP19A1CYP11B2CYP17A1
SCHEMBL22227765 0.97 CYP11B1 (0.67) CYP11B1DHODHCYP19A1CYP11B2CYP17A1
SCHEMBL19762057 0.96 CYP11B1 (0.65) CYP11B1DHODHCYP19A1CYP11B2CYP17A1
SCHEMBL23095158 0.95 CYP11B1 (0.60) CYP11B1DHODHCYP19A1CYP11B2CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3244464-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2020-09-24 US disclosed
EP-3244463-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2020-07-22 EP disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-10559759-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-02-11 US disclosed
US-10276800-B2 Organic electroluminescence device having at least an a node, a hole injection layer, a first hole transport layer. A second hole transport layer a luminous layer, an electron transport layer, and a cathode HODOGAYA CHEMICAL CO., LTD. (JP) 2019-04-30 US disclosed
US-20190006596-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2019-01-03 US disclosed
US-9905775-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-01-04 US disclosed
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2017-11-30 US disclosed
EP-3244464-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3244463-A1 ORGANIC ELECTROLUMINESCENT DEVICE Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-02 US disclosed
EP-3229284-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-10-11 EP disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
EP-3156402-A1 PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-04-19 EP disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 WO disclosed
WO-2016088759-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10276800-B2 Organic electroluminescence device having at least an a node, a hole injection layer, a first hole transport layer. A second hole transport layer a luminous layer, an electron transport layer, and a cathode SLC29A1, SLC29A2, NUDT1 CYP11B1 1848/4885DHODH 290/4885CYP19A1 1602/4885
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 CYP11B1 272/4885DHODH 2619/4885CYP19A1 42/4885
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, KCNH1 CYP11B1 272/4885DHODH 2619/4885CYP19A1 42/4885
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, ARNT CYP11B1 450/4885DHODH 1866/4885CYP19A1 177/4885
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD CYP11B1 1800/4885DHODH 8/4885CYP19A1 1535/4885
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD CYP11B1 1800/4885DHODH 8/4885CYP19A1 1535/4885
US-20190006596-A1 ORGANIC ELECTROLUMINESCENT DEVICE SLC43A1, SLC7A5, SLCO4C1 CYP11B1 1290/4885DHODH 1638/4885CYP19A1 283/4885
US-10559759-B2 Organic electroluminescent device SLC29A2, SLC29A1, SLCO4C1 CYP11B1 1190/4885DHODH 241/4885CYP19A1 1008/4885
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE NUDT1, SLCO4C1, SLC7A5 CYP11B1 1637/4885DHODH 255/4885CYP19A1 1533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.