Sugi Predict

Sugi Predict / Targets / BACH1

BACH1

Transcription regulator protein BACH1 · O14867 · BACH1 on Sugi Atlas →

250 patent compounds predicted against BACH1, 159 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL18937400 SCHEMBL18937400 0.47 2/20
SCHEMBL3811926 SCHEMBL3811926 0.47 2/20
SCHEMBL1688838 SCHEMBL1688838 0.45 2/20
SCHEMBL4859085 SCHEMBL4859085 0.45 2/20
SCHEMBL14268358 SCHEMBL14268358 0.45 2/20
SCHEMBL14268360 SCHEMBL14268360 0.45 2/20
Butyl Isothiocyanate Butyl Isothiocyanate (SCHEMBL28841563) 0.45 2/20
SCHEMBL18911845 SCHEMBL18911845 0.45 2/20
SCHEMBL988586 SCHEMBL988586 0.44 2/20
SCHEMBL6384757 SCHEMBL6384757 0.39 2/20
SCHEMBL18905760 SCHEMBL18905760 0.39 2/20
Butyl Isothiocyanate Butyl Isothiocyanate (SCHEMBL28493037) 0.39 2/20
SCHEMBL10045193 SCHEMBL10045193 0.37 2/20
Butyl Isothiocyanate Butyl Isothiocyanate (SCHEMBL8186071) 0.36 2/20
SCHEMBL18911841 SCHEMBL18911841 0.36 2/20
SCHEMBL484045 SCHEMBL484045 0.56 1/20
SCHEMBL21842754 SCHEMBL21842754 0.56 1/20
SCHEMBL21842756 SCHEMBL21842756 0.54 1/20
SCHEMBL330913 SCHEMBL330913 0.54 1/20
SCHEMBL1233523 SCHEMBL1233523 0.54 1/20

Clinical trials — most relevant to BACH1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Motor Function Efficacy of Pharmacological Treatments Targeting Energy Metabolism, in Parkinson's Patients PHASE4UNKNOWN
Effect of Oral Supplementation With Curcumin (Turmeric) in Patients With Proteinuric Chronic Kidney Disease PHASE3COMPLETED
Bortezomib for Low or Intermediate-1 Myelodysplastic Syndrome (MDS) With p65 Activation PHASE2COMPLETED
Trial of Trientine Plus Pegylated Liposomal Doxorubicin and Carboplatin in Epithelial Ovarian Cancer PHASE1/PHASE2COMPLETED
Effect of Oral Supplementation With Curcumin in Patients With Proteinuric Diabetic Kidney Disease PHASE2UNKNOWN
Clinical Trial With Broccoli Sprout Extract to Patients With Type 2 Diabetes PHASE2COMPLETED
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma PHASE2WITHDRAWN
Broccoli Sprout Extracts Trial to See if NRF2 is Enhanced by Sulforaphane Treatment in Patients With COPD PHASE2COMPLETED
Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy PHASE2RECRUITING
A Study of APX3330 in Patients With Advanced Solid Tumors PHASE1COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease EARLY_PHASE1RECRUITING
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients nanUNKNOWN
Treatment Strategy to Enhance Nrf2 Signaling in Older Adults nanCOMPLETED
Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) nanRECRUITING
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise nanCOMPLETED
GDF 15 in Sickle Cell Disease and Hereditary Spherocytosis nanUNKNOWN
Detection of Krupple Like Factor -1(KLF1/ EKLF) DNA Mutations in Beta Thalassemia Patients nanNOT_YET_RECRUITING
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea nanRECRUITING
Tecfidera Diffusion Tensor Imaging nanCOMPLETED
Cerebral and Anti-inflammatory Response Through Exercise - Mechanisms In Depressive Disorders nanRECRUITING
Human Study of Hydroxytyrosol on Phase II Enzymes in Healthy Subjects nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Identification of Serum Level of Glutathione Peroxidase 4 nanNOT_YET_RECRUITING
BSCU1 and Immune Function nanCOMPLETED
Using Mobile Technology to Improve Self-Regulation nanCOMPLETED
Immune Interactions in Severe Asthma nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a BACH1 binder may also engage these)

ProteinNameSimilarity
P97302 — 1.000 P97302 →
Q9BYV9 — 0.993 Q9BYV9 →
P97303 — 0.990 P97303 →
Q9NWN3 — 0.989 Q9NWN3 →
Q80XI1 — 0.987 Q80XI1 →
Q5FWP7 — 0.987 Q5FWP7 →
Q6GPJ8 — 0.987 Q6GPJ8 →
Q6P1D7 — 0.986 Q6P1D7 →
Q8BHZ4 — 0.986 Q8BHZ4 →
Q86T90 — 0.986 Q86T90 →
Q9CZ62 — 0.986 Q9CZ62 →
O54968 — 0.985 O54968 →
Q60795 — 0.985 Q60795 →
Q3MHT3 — 0.985 Q3MHT3 →
Q6NZK5 — 0.985 Q6NZK5 →
Q5U5Q9 — 0.985 Q5U5Q9 →
Q1W617 — 0.984 Q1W617 →
A0A5K7RLP0 — 0.984 A0A5K7RLP0 →
Q9JKY3 — 0.984 Q9JKY3 →
A0JM80 — 0.984 A0JM80 →
Q99ME3 — 0.984 Q99ME3 →
Q3UZ45 — 0.984 Q3UZ45 →
Q6GQV1 — 0.984 Q6GQV1 →
Q8BUH8 — 0.984 Q8BUH8 →
Q8BG89 — 0.984 Q8BG89 →
Q80Y19 — 0.984 Q80Y19 →
Q8JJ48 — 0.984 Q8JJ48 →
Q5PQK4 — 0.983 Q5PQK4 →
Q96T21 — 0.983 Q96T21 →
P56951 — 0.983 P56951 →