Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.57 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.57 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22229861 | 1.00 | ANPEP (0.57) | ANPEPRNPEPDNPEPLTA4HALPI | |
| SCHEMBL8005620 | 0.90 | ALPI (0.54) | ANPEPRNPEPDNPEPLTA4HALPI | |
| SCHEMBL14691646 | 0.84 | ALPI (0.54) | ANPEPRNPEPDNPEPLTA4HALPI | |
| SCHEMBL28547713 | 0.83 | ACE (0.49) | ANPEPRNPEPDNPEPLTA4H | |
| SCHEMBL10908162 | 0.83 | ANPEP (0.45) | ANPEPRNPEPDNPEPSLC15A1SLC1A3 | |
| SCHEMBL28540563 | 0.82 | ALPI (0.46) | ANPEPRNPEPDNPEPLTA4HALPI | |
| SCHEMBL11151406 | 0.82 | ANPEP (0.56) | ANPEPRNPEPDNPEPLTA4HALPI | |
| SCHEMBL17026707 | 0.81 | ANPEP (0.49) | ANPEPRNPEPDNPEPLTA4HALPI | |
| SCHEMBL28786062 | 0.81 | ANPEP (0.55) | ANPEPRNPEPDNPEPLTA4HALPI | |
| SCHEMBL28786054 | 0.81 | ANPEP (0.55) | ANPEPRNPEPDNPEPLTA4HALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911348-A1 | METHOD OF TREATING CENTRAL NERVOUS SYSTEM DISEASE | L & J Bio Co., Ltd. (KR) | 2021-11-24 | — | — | EP | claimed |
| WO-2020150725-A1 | METHOD OF TREATING CENTRAL NERVOUS SYSTEM DISEASE | L&J BIOSCIENCES INC. (US) | 2020-07-23 | — | — | WO | claimed |
| US-20200230218-A1 | METHOD OF TREATING CENTRAL NERVOUS SYSTEM DISEASE | L & J Bio Co., Ltd. (KR) | 2020-07-23 | — | — | US | claimed |
| CN-113583178-B | Branched sugar-containing polymer-based nanoparticle, and preparation method and application thereof | 四川大学华西医院 | 2023-05-05 | — | — | CN | disclosed |
| EP-3911348-A1 | METHOD OF TREATING CENTRAL NERVOUS SYSTEM DISEASE | L & J Bio Co., Ltd. (KR) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020150725-A1 | METHOD OF TREATING CENTRAL NERVOUS SYSTEM DISEASE | L&J BIOSCIENCES INC. (US) | 2020-07-23 | — | — | WO | disclosed |
| US-20200230218-A1 | METHOD OF TREATING CENTRAL NERVOUS SYSTEM DISEASE | L & J Bio Co., Ltd. (KR) | 2020-07-23 | — | — | US | disclosed |
| CN-106967062-A | The analogs of novel C C 1065 and its conjugate | 辛塔佳股份有限公司 | 2017-07-21 | — | — | CN | disclosed |
| CN-106749665-A | The novel conjugates of the analogs of CC 1065 and bifunctional linker | 辛塔佳有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106492226-A | Tumor-targeting polypeptide anthracycline derivative | 武汉大学苏州研究院 | 2017-03-15 | — | — | CN | disclosed |
| CN-103118679-B | Conjugates of CC-1065 Analogs and Bifunctional Linkers | SYNTARGA B.V. (NL) | 2016-12-14 | — | — | CN | disclosed |
| CN-104587484-A | POLYMERIC SYSTEMS FOR THE DELIVERY OF ANTICANCER DRUGS | REXAHN PHARMACEUTICALS INC | 2015-05-06 | — | — | CN | disclosed |
| CN-102686243-B | Polymeric systems for anticancer agent delivery | REXAHN PHARMACEUTICALS INC | 2015-02-18 | — | — | CN | disclosed |
| CN-103118679-A | Novel conjugates of CC-1065 analogs and bifunctional linkers | SYNTARGA BV | 2013-05-22 | — | — | CN | disclosed |
| CN-102686243-A | Polymeric systems for anticancer agent delivery | REXAHN PHARMACEUTICALS INC | 2012-09-19 | — | — | CN | disclosed |
| CN-102317283-A | Novel CC-1065 analogs and conjugates thereof | SYNTARGA BV | 2012-01-11 | — | — | CN | disclosed |
| CN-101415679-A | Water-soluble CC-1065 analogs and conjugates thereof | SINTAGAR B V (NL) | 2009-04-22 | — | — | CN | disclosed |