SCHEMBL28540563

SCHEMBL28540563

CC(O)CC(=O)N(CC(=O)O)C(=O)C(N)Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.46
PKM P14618 1/20 0.46
PTGS1 P23219 1/20 0.46
XIAP P98170 1/20 0.46
SLC7A5 Q01650 1/20 0.46
SLC15A1 P46059 2/20 0.44
ANPEP P15144 2/20 0.44
RNPEP Q9H4A4 2/20 0.44
DNPEP Q9ULA0 2/20 0.44
LTA4H P09960 2/20 0.43
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
SLC1A1 P43005 1/20 0.41
CPA1 P15085 2/20 0.41
CPB1 P15086 1/20 0.41
CPA3 P15088 1/20 0.41
CPB2 Q96IY4 1/20 0.41
HPGD P15428 1/20 0.40
SLC6A2 P23975 2/20 0.39
TAAR1 Q96RJ0 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8005620 0.86 ALPI (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7587110 0.83 ALPI (0.51) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27426539 0.83 ALPI (0.51) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL14691646 0.83 ALPI (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL22229861 0.82 ANPEP (0.57) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL22229863 0.82 ANPEP (0.57) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL29027552 0.76 MMP2 (0.51) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL11357126 0.76 ALPI (0.56) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL8673016 0.75 SLC7A5 (0.57) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27375801 0.75 SLC7A5 (0.57) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108017555-B Beta-hydroxybutyryl-amino acid compound and preparation method and application thereof 郑州海斯威生物技术有限公司 2021-03-26 CN disclosed