Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.43 |
| ▸ | CTSC | P53634 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | FCER2 | P06734 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021136 | 0.84 | LTA4H (0.45) | ACELTA4HANPEPRNPEPDNPEP | |
| SCHEMBL22229861 | 0.83 | ANPEP (0.57) | LTA4HANPEPRNPEPDNPEP | |
| SCHEMBL22229863 | 0.83 | ANPEP (0.57) | LTA4HANPEPRNPEPDNPEP | |
| SCHEMBL5915244 | 0.80 | PSMB5 (0.45) | ACEPSMB5MMP1MMP2 | |
| SCHEMBL11575487 | 0.78 | CTSB (0.39) | ACELTA4H | |
| SCHEMBL16501164 | 0.77 | LTA4H (0.55) | ACELTA4HPSMB5CTSCMMP1 | |
| SCHEMBL27373873 | 0.77 | CTSC (0.42) | ACECTSCMMP2MMP9 | |
| SCHEMBL24235659 | 0.75 | PSMB5 (0.58) | ACEPSMB5MMP1FCER2MMP2 | |
| SCHEMBL15924685 | 0.75 | MC4R (0.47) | ACEFCER2MMP9 | |
| Glycylleucylphenylalanine SCHEMBL4281374 | 0.74 | ACE (0.62) | ACEMMP2MMP7MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749665-B | Conjugates of CC-1065 analogs and bifunctional linkers | 辛塔佳有限公司 | 2021-03-26 | — | — | CN | disclosed |