SCHEMBL222299

SCHEMBL222299

Nc1ccc2ccccc2c1SSc1c(N)ccc2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.63
PAK1 Q13153 1/20 0.63
ALDH1A1 P00352 4/20 0.50
HSD17B10 Q99714 4/20 0.50
TSHR P16473 3/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
KEAP1 Q14145 1/20 0.50
CYP2A6 P11509 3/20 0.48
TDP1 Q9NUW8 1/20 0.48
HPRT1 P00492 2/20 0.47
PTPN22 Q9Y2R2 1/20 0.41
HDAC3 O15379 1/20 0.41
IDO1 P14902 1/20 0.41
EP300 Q09472 1/20 0.41
KAT2B Q92831 1/20 0.41
KAT8 Q9H7Z6 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP1B1 Q16678 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3788072 0.87 USP2 (0.50) USP2PAK1ALDH1A1HSD17B10TSHR
SCHEMBL20812876 0.86 USP2 (0.49) USP2PAK1ALDH1A1HSD17B10TSHR
SCHEMBL222310 0.86 USP2 (0.49) USP2PAK1ALDH1A1HSD17B10TSHR
SCHEMBL11718402 0.83 USP2 (0.48) USP2PAK1ALDH1A1HSD17B10TSHR
SCHEMBL4907161 0.77 USP2 (1.00) USP2PAK1ALDH1A1HSD17B10TSHR
SCHEMBL29354769 0.77 USP2 (1.00) USP2PAK1ALDH1A1HSD17B10TSHR
SCHEMBL11717742 0.75 POLB (0.50) USP2PAK1ALDH1A1HSD17B10TSHR
SCHEMBL31390038 0.73 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP3A4HPGD
SCHEMBL455943 0.73 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP3A4HPGD
SCHEMBL64806 0.73 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
US-10933285-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2021-03-02 US disclosed
US-20200197757-A1 MULTI-LAYER CORE GOLF BALL ACUSHNET COMPANY (US) 2020-06-25 US disclosed
US-10596419-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2020-03-24 US disclosed
US-20200086174-A1 A GOLF BALL COMPRISING A VERY-LOW MELT FLOW INNER COVER LAYER COMPOSITION JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2020-03-19 US disclosed
US-20200047033-A1 MULTI-LAYER CORE GOLF BALL ACUSHNET COMPANY (US) 2020-02-13 US disclosed
US-10478674-B2 Golf ball comprising a very-low melt flow inner cover layer composition ACUSHNET COMPANY (US) 2019-11-19 US disclosed
US-10478675-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2019-11-19 US disclosed
US-20020006837-A1 Wound golf ball having cast polyurethane cover ACUSHNET COMPANY 2002-01-17 US disclosed
WO-2000038794-A9 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET CO (US) 2001-11-01 WO disclosed
US-20010024982-A1 Thin-layer-covered multilayer golf ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2001-09-27 US disclosed
US-6291592-B1 HARDNESS, STIFFNESS ACUSHNET COMPANY 2001-09-18 US disclosed
WO-2000038794-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038795-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AROMATIC CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038793-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING ELEMENTAL CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
US-5816939-A AGING RESISTANCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1998-10-06 US disclosed