Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246541 | 0.85 | TAAR1 (0.45) | HSPA5KMT2ATAAR1 | |
| SCHEMBL3243401 | 0.85 | IDO1 (0.48) | PNMTIDO1TAAR1PKM | |
| SCHEMBL3245734 | 0.85 | TAAR1 (0.46) | IDO1TAAR1 | |
| SCHEMBL1287474 | 0.84 | CALM1 (0.52) | CALM1MEN1CYP3A4KMT2AHTR2A | |
| SCHEMBL6288770 | 0.82 | CYP2C19 (0.50) | CYP3A4MAPTTDP1TAAR1 | |
| SCHEMBL5869932 | 0.81 | TAAR1 (0.35) | HSPA5HTR2APNMTIDO1TAAR1 | |
| SCHEMBL3244848 | 0.80 | IDO1 (0.50) | MAPTIDO1TAAR1 | |
| SCHEMBL3249477 | 0.80 | IDO1 (0.48) | KMT2ATDP1IDO1 | |
| SCHEMBL27713785 | 0.80 | CYP19A1 (0.41) | MAPT | |
| SCHEMBL525380 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130078283-A1 | NOVEL AMPHIPHILES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-03-28 | — | — | US | disclosed |
| WO-2011084106-A1 | NOVEL AMPHIPHILES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130078283-A1 | NOVEL AMPHIPHILES | OLA1, SMARCA1, SMARCA2 | HSPA5 1570/4885CALM1 2936/4885GPR84 770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.