Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223002 | 0.84 | HSPA5 (0.46) | CALM1HTR2AMEN1KMT2AKEAP1 | |
| SCHEMBL28025384 | 0.82 | TP53 (0.46) | HTR2ASMN1; SMN2KEAP1 | |
| SCHEMBL5852567 | 0.82 | CYP3A4 (0.52) | HTR2AKEAP1CYP3A4L3MBTL1 | |
| SCHEMBL972711 | 0.81 | CALM1 (0.69) | CALM1HTR2ABCL2BCL2L1ALOX5 | |
| SCHEMBL10653799 | 0.81 | HTR2A (0.42) | CALM1HTR2ABCL2BCL2L1ALOX5 | |
| SCHEMBL2028062 | 0.81 | BCL2 (0.50) | HTR2ABCL2BCL2L1ALOX5KEAP1 | |
| SCHEMBL1287637 | 0.78 | HTR1A (0.48) | HTR2AHPGDSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL27713690 | 0.78 | TACR1 (0.35) | BCL2BCL2L1CYP3A4 | |
| SCHEMBL3246541 | 0.76 | TAAR1 (0.45) | HPGDKMT2A | |
| SCHEMBL10799851 | 0.75 | CALM1 (0.52) | CALM1HTR2ABCL2BCL2L1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | claimed |
| EP-4204400-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | Fibrogen, Inc. (US) | 2023-07-05 | — | — | EP | claimed |
| US-20040116410-A1 | Diazepinones as antiviral agents | CHO HIDETSURA (JP) | 2004-06-17 | — | — | US | claimed |
| US-5885548-A | Multiply substituted DTPA derivatives and their metal complexes, and their metal complexes, pharmaceutical agents that contain these complexes, their use in diagnosis and therapy, as well as process for the production of pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | claimed |
| US-5746995-A | DTPA derivatives substituted in a novel way, their metal complexes, and their use in diagnosis and therapy | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-05 | — | — | US | claimed |
| US-20240208992-A1 | MACROCYCLES AS CFTR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-27 | — | — | US | disclosed |
| WO-2024048076-A1 | APPARATUS FOR PRODUCING FIBER-REINFORCED COMPOSITE SHEET AND METHOD FOR PRODUCING FIBER-REINFORCED COMPOSITE SHEET | DIC株式会社 | 2024-03-07 | — | — | WO | disclosed |
| WO-2023163144-A9 | OPTICAL LAMINATE FOR OLED DISPLAY DEVICE | 日東電工株式会社 | 2024-02-01 | — | — | WO | disclosed |
| WO-2024010041-A1 | ADHESIVE AND ADHESIVE SHEET | 日東電工株式会社 | 2024-01-11 | — | — | WO | disclosed |
| WO-2024010042-A1 | PRESSURE-SENSITIVE ADHESIVE AND PRESSURE-SENSITIVE ADHESIVE SHEET | 日東電工株式会社 | 2024-01-11 | — | — | WO | disclosed |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | disclosed |
| WO-2024004861-A1 | ACTIVE ENERGY RAY-CURABLE COMPOSITION, AND CURED PRODUCT THEREOF | DIC株式会社 | 2024-01-04 | — | — | WO | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| WO-1996000241-A1 | PROCESS FOR THE PREPARATION OF PEPTIDE TRISULFIDES | PHARMACIA & UPJOHN AB (SE) | 1996-01-04 | — | — | WO | disclosed |
| EP-0662965-A1 | 1,2-DISUBSTITUTED ETHYL AMIDES AS INHIBITORS OF ACAT | SCHERING CORPORATION (US) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994006784-A1 | 1,2-DISUBSTITUTED ETHYL AMIDES AS INHIBITORS OF ACAT | SCHERING CORPORATION (US) | 1994-03-31 | — | — | WO | disclosed |
| US-4939186-A | Aliphatic or aromatic alkene hydrocarbons or oxy compounds polycarbonateester copolymers, blends | GENERAL ELECTRIC COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4920091-A | CONTAINING SALICYLIC ACID DERIVATIVE AS ELECTRON ACCEPTING COLOR DEVELOPER; STABLE IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-24 | — | — | US | disclosed |
| US-4847377-A | ANTIHYPERPROLIFERATIVE SKIN DISEASES | SCHERING CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| US-4816458-A | TOPICAL ADMINISTERING | SCHERING CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208992-A1 | MACROCYCLES AS CFTR MODULATORS | CFTR, PKD1, ARRB1 | CALM1 2526/4885HTR2A 1200/4885BCL2 3433/4885 |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | KDM5C, KDM5B, KDM5A | CALM1 1625/4885HTR2A 3818/4885BCL2 2886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.