SCHEMBL2223115

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22452839	0.87	POLB (0.59)	MAPTLMNAPOLBHRH3GPR119
	SCHEMBL4554527	0.85	POLB (0.61)	POLBGPR119KITGBA1TRPV1
	SCHEMBL29089138	0.84	POLB (0.56)	MAPTLMNAPOLBNPSR1HRH3
	SCHEMBL11892882	0.84	POLB (0.60)	POLBGPR119KITGBA1TRPV1
	SCHEMBL2223119	0.83	MAPT (0.62)	MAPTLMNAPOLBKDM4ENPSR1
	SCHEMBL14488641	0.82	MAPT (0.72)	MAPTLMNAPOLBKDM4ENPSR1
	SCHEMBL12516130	0.82	MAPT (0.72)	MAPTLMNAPOLBKDM4ENPSR1
	SCHEMBL31651830	0.82	POLB (0.52)	POLBHRH3GPR119KITGBA1
	SCHEMBL31651807	0.81	POLB (0.54)	MAPTPOLBL3MBTL1HRH3GPR119
	SCHEMBL12516839	0.80	MAPT (0.47)	MAPTLMNAPOLBKDM4ENPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.