Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GBA1 | P04062 | 2/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.51 |
| ▸ | CKS1B | P61024 | 2/20 | 0.51 |
| ▸ | SKP1 | P63208 | 2/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.51 |
| ▸ | KIT | P10721 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | DTYMK | P23919 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11892882 | 0.89 | POLB (0.60) | POLBGBA1GPR119CKS1BSKP1 | |
| SCHEMBL22452839 | 0.88 | POLB (0.59) | POLBGBA1GPR119CKS1BSKP1 | |
| SCHEMBL2560776 | 0.86 | POLB (0.56) | POLBGBA1GPR119CKS1BSKP1 | |
| SCHEMBL2223115 | 0.85 | MAPT (0.63) | POLBGBA1GPR119CKS1BSKP1 | |
| SCHEMBL29089138 | 0.85 | POLB (0.56) | POLBKMT2AGBA1GPR119CKS1B | |
| SCHEMBL2715768 | 0.85 | POLB (0.57) | POLBGBA1GPR119CKS1BSKP1 | |
| SCHEMBL3436722 | 0.85 | POLB (0.57) | POLBGBA1GPR119CKS1BSKP1 | |
| SCHEMBL31046329 | 0.85 | POLB (0.57) | POLBGBA1GPR119CKS1BSKP1 | |
| SCHEMBL5863376 | 0.84 | ACHE (0.48) | POLBKMT2AGBA1GPR119CKS1B | |
| SCHEMBL30645549 | 0.84 | POLB (0.57) | POLBKMT2AGBA1GPR119CKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115175901-A | Compounds and methods for targeted degradation of androgen receptor | 阿尔维纳斯运营股份有限公司 | 2022-10-11 | — | — | CN | disclosed |
| EP-2125748-A2 | ACYLAMINOPYRAZOLES AS FGFR INHIBITORS | AstraZeneca AB (SE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008075068-A2 | ACYLAMINOPYRAZOLES AS FGFR INHIBITORS | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |
| US-5854245-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-29 | — | — | US | disclosed |