SCHEMBL22231920

SCHEMBL22231920

CCN(C)C=Nc1cc(Cl)cc(Nc2ccc(OC)c(F)c2)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GALR2 O43603 2/20 0.37
BCL6 P41182 2/20 0.34
TUBB1 Q9H4B7 1/20 0.34
ABCG2 Q9UNQ0 2/20 0.34
ABCB1 P08183 1/20 0.34
ABCC1 P33527 1/20 0.34
P2RX3 P56373 1/20 0.33
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
KCNH2 Q12809 1/20 0.33
GALR1 P47211 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
EGFR P00533 3/20 0.32
KDR P35968 1/20 0.32
BACE2 Q9Y5Z0 1/20 0.32
MEN1 O00255 2/20 0.31
MAPT P10636 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 2/20 0.31
HTT P42858 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22231917 1.00 GALR2 (0.37) GALR2BCL6TUBB1ABCG2ABCB1
SCHEMBL22232249 0.90 GALR2 (0.38) GALR2BCL6TUBB1ABCG2ABCB1
SCHEMBL22232252 0.90 GALR2 (0.38) GALR2BCL6TUBB1ABCG2ABCB1
SCHEMBL22231885 0.89 GALR2 (0.41) GALR2BCL6TUBB1ABCG2ABCB1
SCHEMBL22231883 0.89 GALR2 (0.41) GALR2BCL6TUBB1ABCG2ABCB1
SCHEMBL28637700 0.86 GALR2 (0.37) GALR2BCL6TUBB1ABCG2ABCB1
SCHEMBL22232170 0.85 GALR2 (0.39) GALR2BCL6TUBB1ABCG2ABCB1
SCHEMBL22232172 0.85 GALR2 (0.39) GALR2BCL6TUBB1ABCG2ABCB1
SCHEMBL22231880 0.84 SLC2A1 (0.36) NPSR1KDRMEN1MAPTKMT2A
SCHEMBL22231881 0.84 SLC2A1 (0.36) NPSR1KDRMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US claimed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US claimed
EP-3911629-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2021-11-24 EP claimed
WO-2020148617-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2020-07-23 WO claimed
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US disclosed
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP disclosed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US disclosed
EP-3911629-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2021-11-24 EP disclosed
WO-2020148617-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2020-07-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF H1-3, PRMT7, PFAS GALR2 2951/4885BCL6 4167/4885TUBB1 2068/4885
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof CBR1, CBR3, HCCS GALR2 679/4885BCL6 786/4885TUBB1 2722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.