SCHEMBL22232249

SCHEMBL22232249

CCN(C)/C=N/c1cc(F)cc(Nc2ccc(OC)c(F)c2)c1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GALR2 O43603 4/20 0.38
TUBB1 Q9H4B7 3/20 0.35
ABCG2 Q9UNQ0 2/20 0.35
ABCB1 P08183 1/20 0.35
ABCC1 P33527 1/20 0.35
GALR1 P47211 2/20 0.33
KCNH2 Q12809 1/20 0.32
PIK3CA P42336 1/20 0.32
BCL6 P41182 1/20 0.31
KDM4E B2RXH2 2/20 0.31
DHFR P00374 1/20 0.31
ALDH1A1 P00352 2/20 0.31
JAK2 O60674 1/20 0.31
JAK1 P23458 1/20 0.31
TYK2 P29597 1/20 0.31
JAK3 P52333 1/20 0.31
CTSV O60911 1/20 0.31
CTSL P07711 1/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22232252 1.00 GALR2 (0.38) GALR2TUBB1ABCG2ABCB1ABCC1
SCHEMBL22231883 0.91 GALR2 (0.41) GALR2TUBB1ABCG2ABCB1ABCC1
SCHEMBL22231885 0.91 GALR2 (0.41) GALR2TUBB1ABCG2ABCB1ABCC1
SCHEMBL22231920 0.90 GALR2 (0.37) GALR2TUBB1ABCG2ABCB1ABCC1
SCHEMBL22231917 0.90 GALR2 (0.37) GALR2TUBB1ABCG2ABCB1ABCC1
SCHEMBL22232233 0.88 RAPGEF4 (0.35) KDM4EDHFRRAB9A
SCHEMBL22232234 0.88 RAPGEF4 (0.35) KDM4EDHFRRAB9A
SCHEMBL22231748 0.83 HTR2C (0.38) PIK3CAHTT
SCHEMBL22231744 0.83 HTR2C (0.38) PIK3CAHTT
SCHEMBL22232436 0.82 RAPGEF4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US claimed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US claimed
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US disclosed
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP disclosed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US disclosed
EP-3911629-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2021-11-24 EP disclosed
WO-2020148617-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2020-07-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF H1-3, PRMT7, PFAS GALR2 2951/4885TUBB1 2068/4885ABCG2 219/4885
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof CBR1, CBR3, HCCS GALR2 679/4885TUBB1 2722/4885ABCG2 466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.