SCHEMBL4199968

SCHEMBL4199968

O=C(O)CNC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.56
KIF11 P52732 1/20 0.52
CYP2C19 P33261 1/20 0.47
HIF1A Q16665 1/20 0.47
CYP1A2 P05177 1/20 0.41
ABAT P80404 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
ALOX15 P16050 2/20 0.40
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11417864 0.89 KCNN4 (0.46) KCNN4KIF11CYP2C19HIF1AABAT
SCHEMBL28544425 0.85 KCNN4 (0.55) KCNN4KIF11CYP2C19HIF1ACYP1A2
SCHEMBL30610089 0.84 KIF11 (0.49) KCNN4KIF11ALOX15KMT2AKDM4E
SCHEMBL14356107 0.84 KIF11 (0.49) KCNN4KIF11ALOX15KMT2AKDM4E
Hydrochloric Acid SCHEMBL10984929 0.84 KCNN4 (0.48) KCNN4KIF11CYP2C19HIF1ACYP1A2
Aspartic Acid SCHEMBL21596241 0.83 KIF11 (0.47) KIF11
SCHEMBL22916699 0.82 KCNN4 (0.52) KCNN4KIF11CYP2C19HIF1AHDAC3
SCHEMBL2223266 0.82 KCNN4 (0.44) KCNN4KIF11CYP2C19HIF1ACYP1A2
SCHEMBL10065920 0.81 KCNN4 (0.60) KCNN4KIF11CYP2C19HIF1ACYP1A2
SCHEMBL4211757 0.81 KIF11 (0.57) KCNN4KIF11CYP2C19HIF1AHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114401981-B Glucagon production method 北京费森尤斯卡比医药有限公司 2024-11-08 CN claimed
CN-114560907-B Preparation method of glutathione impurity 武汉绿合医药科技有限公司 2024-08-09 CN claimed
CN-117024528-B Preparation method of Retatrutide 杭州信海医药科技有限公司 2024-03-22 CN claimed
CN-111018963-B Preparation method of glucagon 中肽生化有限公司 2023-11-24 CN claimed
CN-117024528-A Preparation method of Retatrutide 杭州信海医药科技有限公司 2023-11-10 CN claimed
CN-117007704-A Liquid phase analysis method for quantitatively detecting isomer content in dipeptide 南京汉欣医药科技有限公司 2023-11-07 CN claimed
CN-115975057-B Solid phase synthesis method of trastuzumab 杭州信海医药科技有限公司 2023-05-16 CN claimed
CN-115975057-A Solid-phase synthesis method of clodotoxin 杭州信海医药科技有限公司 2023-04-18 CN claimed
CN-113173987-B Method for synthesizing linatide 汉肽生物医药集团有限公司 2022-11-29 CN claimed
CN-113735955-B Preparation method of conus anti-wrinkle agent 汉肽生物医药集团有限公司 2022-10-28 CN claimed
CN-114790236-A Synthetic method of GCGR/GLP-1R double-target-point agonist polypeptide 深圳市图微安创科技开发有限公司 2022-07-26 CN claimed
CN-114560907-A Preparation method of glutathione impurity 武汉绿合医药科技有限公司 2022-05-31 CN claimed
CN-113527545-B Beta-cyclodextrin polyrotaxane with accurate insertion amount, preparation method and application thereof 北京理工大学 2022-05-17 CN claimed
CN-114401981-A Process for producing glucagon 北京费森尤斯卡比医药有限公司 2022-04-26 CN claimed
CN-113527545-A Beta-cyclodextrin polyrotaxane with accurate insertion amount, preparation method and application thereof 北京理工大学 2021-10-22 CN claimed
CN-103509083-B A kind of wide spectrum beta-lactamase fluorogenic substrate and its preparation method and application 王郁生 2016-06-08 CN claimed
CN-103509083-A Broad-spectrum beta-lactamase fluorescent substrate, and preparation method and application thereof WANG YUSHENG 2014-01-15 CN claimed
EP-0284966-B1 Processes for the preparation of benzo (chalcogeno)[4,3,2-CD] indazoles WARNER-LAMBERT COMPANY (US) 1992-01-02 EP claimed
US-4806654-A Processes for the preparation of benzo(chalcogeno)(4,3,2-cd)indazoles and intermediates thereof WARNER-LAMBERT COMPANY (US) 1989-02-21 US claimed
EP-0284966-A1 Processes for the preparation of benzo (chalcogeno)[4,3,2-CD] indazoles WARNER-LAMBERT COMPANY (US) 1988-10-05 EP claimed