Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyrrolidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrolidine SCHEMBL5683314 | 1.00 | ALDH1A1 (0.53) | — | |
| Piperidine SCHEMBL66142 | 0.97 | — | — | |
| Piperidine SCHEMBL27734261 | 0.94 | ALDH1A1 (0.56) | — | |
| Piperidine SCHEMBL6836703 | 0.94 | ALDH1A1 (0.56) | — | |
| Piperidine SCHEMBL28352932 | 0.94 | ALDH1A1 (0.56) | — | |
| Azetidine SCHEMBL22833205 | 0.93 | ALDH1A1 (0.50) | — | |
| Azetidine SCHEMBL1500479 | 0.93 | — | — | |
| Alcohol SCHEMBL27962627 | 0.90 | CXCR4 (0.60) | — | |
| Aziridine SCHEMBL64046 | 0.89 | — | — | |
| Pyrrolidine SCHEMBL17377306 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004697-A | Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material | 同济大学 | 2025-05-16 | — | — | CN | claimed |
| CN-111638632-B | Photoresist reworking liquid composition for CF procedure | 福建省佑达环保材料有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-114292758-A | Aspergillus TR15 derived from suaeda glauca and application thereof | 青岛农业大学 | 2022-04-08 | — | — | CN | claimed |
| CN-113493628-A | Quantum dot ink and preparation method of quantum dot film | TCL科技集团股份有限公司 | 2021-10-12 | — | — | CN | claimed |
| CN-111704963-A | Water-based cleaning agent for cleaning liquid crystal | 福建省佑达环保材料有限公司 | 2020-09-25 | — | — | CN | claimed |
| CN-111638632-A | Photoresist reworking liquid composition for CF procedure | 福建省佑达环保材料有限公司 | 2020-09-08 | — | — | CN | claimed |
| CN-110874026-A | Stripping liquid composition for color filter and method for using same | 易案爱富科技有限公司 | 2020-03-10 | — | — | CN | claimed |
| CN-108508712-A | Anticorrosive additive stripping liquid controlling composition | 东友精细化工有限公司 | 2018-09-07 | — | — | CN | claimed |
| US-10026993-B2 | Method for synthesizing ionic liquids having a carbonate functional group and ionic liquids thus obtained | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2018-07-17 | — | — | US | claimed |
| US-9758507-B2 | Chiral synthesis of pyrrolidine core compounds en route to neuronal nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2017-09-12 | — | — | US | claimed |
| US-20150380771-A1 | METHOD FOR SYNTHESIZING IONIC LIQUIDS HAVING A CARBONATE FUNCTIONAL GROUP AND IONIC LIQUIDS THUS OBTAINED | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-12-31 | — | — | US | claimed |
| US-9212161-B2 | Chiral synthesis of pyrrolidine core compounds en route to neuronal nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2015-12-15 | — | — | US | claimed |
| US-20140228578-A1 | Chiral Synthesis of Pyrrolidine Core Compounds en route to Neuronal Nitric Oxide Synthase Inhibitors | NORTHWESTERN UNIVERSITY (US) | 2014-08-14 | — | — | US | claimed |
| US-20120004415-A1 | Chiral Synthesis of Pyrrolidine Core Compounds en route to Neuronal Nitric Oxide Synthase Inhibitors | NORTHWESTERN UNIVERSITY | 2012-01-05 | — | — | US | claimed |
| WO-2012003427-A2 | CHIRAL SYNTHESIS OF PYRROLIDINE CORE COMPOUNDS EN ROUTE TO NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NORTHWESTERN UNIVERSITY (US) | 2012-01-05 | — | — | WO | claimed |
| CN-1764482-B | Vascular stent | NOBILL BIOLOG INST CO LTD | 2011-01-19 | — | — | CN | claimed |
| US-20070276472-A1 | Vascular Stent | MEDTRONIC, INC. | 2007-11-29 | — | — | US | claimed |
| CN-1764482-A | Vascular stent | BAYCO TECH LTD (GB) | 2006-04-26 | — | — | CN | claimed |
| EP-1610838-A1 | VASCULAR STENT | Bayco Tech Limited (GB) | 2006-01-04 | — | — | EP | claimed |
| WO-2004087234-A1 | VASCULAR STENT | BAYCO TECH LIMITED (GB) | 2004-10-14 | — | — | WO | claimed |