Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Aziridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL9506704 | 0.96 | ALDH1A1 (0.50) | — | |
| Piperazine SCHEMBL1485419 | 0.96 | — | — | |
| Aziridine SCHEMBL27979623 | 0.92 | — | — | |
| Piperazine SCHEMBL28015400 | 0.92 | ALDH1A1 (0.46) | — | |
| Piperazine SCHEMBL22092466 | 0.92 | ALDH1A1 (0.46) | — | |
| Piperazine SCHEMBL29044668 | 0.92 | ALDH1A1 (0.46) | — | |
| Cyclohexane SCHEMBL28639868 | 0.89 | ALDH1A1 (0.44) | — | |
| Pyrrolidine SCHEMBL5683314 | 0.89 | ALDH1A1 (0.53) | — | |
| Pyrrolidine SCHEMBL222328 | 0.89 | — | — | |
| Azetidine SCHEMBL1500479 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1088 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119799083-A | Paint for preventing oxidation passivation of steel surface and preparation method and application thereof | 陕西中涂联涂料科技有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-118304852-A | Preparation and application of carbon-nitrogen co-doped zinc oxide nanocomposite | 兰州理工大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118179603-A | Composite material for degrading dye as well as preparation method and application thereof | 山东太阳纸业股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| US-20240182683-A1 | STABILIZER COMPOSITION, USE OF THE STABILIZER COMPOSITION, METHOD FOR STABILIZING CONDENSATION POLYMERS AGAINST HYDROLYTIC DEGRADATION, AND HYDROLYSIS-STABILIZED COMPOSITION AND MOLDING OR MOLDED PART CONSISTING THEREOF | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2024-06-06 | — | — | US | claimed |
| CN-115650229-B | Production process of active carbon rod in water treatment device | 亳州市亚珠新材料有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-115644182-B | Chiral nano antibacterial material with autofluorescence/pH double response and preparation method and application thereof | 南京农业大学 | 2024-04-02 | — | — | CN | claimed |
| CN-117283185-A | High-stability lead-free solder paste without inner cover and preparation method thereof | 深圳市宇航金属新材料有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-114261963-B | Preparation method of functionalized graphite flake compound | 陕西师范大学 | 2023-08-11 | — | — | CN | claimed |
| CN-116554469-A | Phosphorus-sulfur synergistic macromolecular flame retardant, preparation method thereof and application thereof in polylactic acid material | 扬州惠通生物新材料有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116288743-A | Oligonucleotide ink-jet printing method | 北京铭毅智造科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| US-7727707-B2 | Barrier film material and pattern formation method using the same | PANASONIC CORPORATION (JP) | 2010-06-01 | — | — | US | claimed |
| CN-1285100-C | Pattern formation method | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2006-11-15 | — | — | CN | claimed |
| US-20060127812-A1 | Barrier film material and pattern formation method using the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. | 2006-06-15 | — | — | US | claimed |
| EP-1669804-A2 | Barrier film material and pattern formation method using the same | Matsushita Electric Industries Co., Ltd. (JP) | 2006-06-14 | — | — | EP | claimed |
| CN-1786820-A | Barrier film material and pattern formation method using the same | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2006-06-14 | — | — | CN | claimed |
| US-6872787-B2 | Post-treatment of a polymeric composition | ISP INVESTMENTS INC. (US) | 2005-03-29 | — | — | US | claimed |
| CN-1574218-A | Pattern formation method | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2005-02-02 | — | — | CN | claimed |
| WO-2002012185-A1 | PROCESS FOR PREPARING 2,3-DIAMINOPROPANOLS AND SYNTHESIS OF OTHER COMPOUNDS USING 2,3-DIAMINOPROPANOLS | CHEMBIONEX CO., LTD. (KR) | 2002-02-14 | — | — | WO | claimed |
| US-5712331-A | Curable epoxy compositions containing aziridine in supercritical fluid carbon dioxide | ROCKWELL INTERNATIONAL CORPORATION (US) | 1998-01-27 | — | — | US | claimed |
| EP-0758662-A2 | Curable epoxy compositions containing aziridine | ROCKWELL INTERNATIONAL CORPORATION (US) | 1997-02-19 | — | — | EP | claimed |