SCHEMBL22233265

SCHEMBL22233265

NC1CC(NC(=O)O)CC(NC(=O)O)C1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.35
SLC6A12 P48065 3/20 0.31
SLC6A11 P48066 3/20 0.31
SLC6A13 Q9NSD5 3/20 0.31
KDM1A O60341 1/20 0.31
ATM Q13315 1/20 0.30
SMYD3 Q9H7B4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3780790 0.97
SCHEMBL3780792 0.97
SCHEMBL15205467 0.97
Hydrochloric Acid SCHEMBL21222636 0.95 GABRR1 (0.35) GABRR1SLC6A12SLC6A11SLC6A13KDM1A
Hydrochloric Acid SCHEMBL21222634 0.95 GABRR1 (0.35) GABRR1SLC6A12SLC6A11SLC6A13KDM1A
SCHEMBL23573431 0.87 ATM (0.36) GABRR1ATM
SCHEMBL4196561 0.81 SMYD3 (0.39) GABRR1SMYD3
SCHEMBL3759316 0.81 SMYD3 (0.39) GABRR1SMYD3
SCHEMBL18987658 0.81 SMYD3 (0.39) GABRR1SMYD3
SCHEMBL4930315 0.81 SMYD3 (0.39) GABRR1SMYD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159491-A1 Antimicrobial Compounds and Methods NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-05-25 US disclosed
EP-3911644-A1 ANTIMICROBIAL COMPOUNDS AND METHODS Curza Global LLC (US) 2021-11-24 EP disclosed
WO-2020150385-A1 ANTIMICROBIAL COMPOUNDS AND METHODS CURZA GLOBAL, LLC (US) 2020-07-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159491-A1 Antimicrobial Compounds and Methods MPO, NISCH, RPN2 GABRR1 3827/4885SLC6A12 850/4885SLC6A11 3846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.