Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 10/20 | 0.35 |
| ▸ | ACE | P12821 | 5/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21358235 | 0.73 | CYP1A2 (0.47) | GAAMAPTMMEALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL14741343 | 0.72 | CYP1A2 (0.46) | GAAMAPTMMEALDH1A1TP53 | |
| SCHEMBL5265048 | 0.70 | GAA (0.41) | GAAMAPTMMEACE | |
| SCHEMBL8129742 | 0.70 | GAA (0.41) | GAAMAPTMMEACE | |
| SCHEMBL29831598 | 0.69 | GAA (0.69) | GAAMAPTMMEACEALDH1A1 | |
| SCHEMBL1531662 | 0.69 | GAA (0.69) | GAAMAPTMMEACEALDH1A1 | |
| SCHEMBL1150614 | 0.69 | GAA (0.69) | GAAMAPTMMEACEALDH1A1 | |
| SCHEMBL444953 | 0.69 | GAA (0.69) | GAAMAPTMMEACEALDH1A1 | |
| Hydrochloric Acid SCHEMBL11047643 | 0.68 | GAA (0.67) | GAAMAPTMMEACEALDH1A1 | |
| Hydrochloric Acid SCHEMBL3157936 | 0.68 | GAA (0.67) | GAAMAPTMMEACEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911653-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020150366-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-07-23 | — | — | WO | disclosed |