Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 9/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22235832 | 0.93 | ROCK2 (0.35) | ROCK2FAAHKDM1AMAOBRCOR1 | |
| SCHEMBL30276490 | 0.89 | JAK1 (0.36) | ROCK2FAAHKDM1AMAOBRCOR1 | |
| SCHEMBL22234110 | 0.88 | DPP7 (0.42) | DPP7 | |
| SCHEMBL22248692 | 0.87 | CYP2D6 (0.42) | FAAHPOLBKDM1AMAOBRCOR1 | |
| SCHEMBL22236184 | 0.85 | POLB (0.36) | ROCK2FAAHPOLB | |
| SCHEMBL22248411 | 0.84 | CXCR4 (0.39) | FAAHPOLB | |
| SCHEMBL22254542 | 0.83 | ROCK2 (0.36) | ROCK2FAAHPOLBKDM1AMAOB | |
| SCHEMBL22254138 | 0.82 | ROCK2 (0.34) | ROCK2FAAHPOLBABL1RIN1 | |
| SCHEMBL22248664 | 0.82 | HPGD (0.44) | FAAHKDM1AMAOBRCOR1 | |
| SCHEMBL30276586 | 0.82 | NAMPT (0.37) | ROCK2FAAHKDM1AMAOBRCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911643-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | Curza Global LLC (US) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |