Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 9/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248664 | 0.93 | HPGD (0.44) | CYP2D6KDM1AMAOBRCOR1CYP1A2 | |
| SCHEMBL22249119 | 0.92 | KDM1A (0.45) | CYP2D6KDM1AMAOBRCOR1CYP1A2 | |
| SCHEMBL22248411 | 0.89 | CXCR4 (0.39) | FAAHPOLBMEN1KMT2A | |
| SCHEMBL22248616 | 0.89 | KDM1A (0.38) | CYP2D6KDM1AMAOBRCOR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL30276477 | 0.89 | KDM1A (0.38) | CYP2D6KDM1AMAOBRCOR1CYP1A2 | |
| SCHEMBL22254542 | 0.88 | ROCK2 (0.36) | KDM1AMAOBRCOR1FAAHPOLB | |
| SCHEMBL22248665 | 0.88 | KDM1A (0.37) | CYP2D6KDM1AMAOBRCOR1CYP1A2 | |
| SCHEMBL22254138 | 0.87 | ROCK2 (0.34) | FAAHPOLB | |
| SCHEMBL22235665 | 0.87 | ROCK2 (0.34) | KDM1AMAOBRCOR1FAAHPOLB | |
| SCHEMBL22249112 | 0.86 | MCHR1 (0.38) | CYP2D6KDM1AMAOBRCOR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |