SCHEMBL22236152

SCHEMBL22236152

CCCCN(C(=O)O)C1C2CNCC21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
SIGMAR1 Q99720 2/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA9 Q16790 2/20 0.33
ALDH1A1 P00352 3/20 0.33
KDM5A P29375 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
USP2 O75604 1/20 0.33
GAA P10253 1/20 0.33
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP8 P22894 1/20 0.32
S1PR3 Q99500 2/20 0.31
GNAI3 P08754 1/20 0.31
GNAO1 P09471 1/20 0.31
GNAI1 P63096 1/20 0.31
CTSD P07339 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13736459 0.73 L3MBTL1 (0.35) L3MBTL1SIGMAR1CA12CA1CA9
SCHEMBL1221462 0.72 SLC6A2 (0.47)
SCHEMBL3821799 0.72 SLC6A2 (0.47)
SCHEMBL28246290 0.72 SLC6A2 (0.47)
SCHEMBL3818321 0.71 SLC6A4 (0.44) L3MBTL1SIGMAR1GNAI3GNAO1GNAI1
SCHEMBL2875169 0.70 SLC6A2 (0.41) L3MBTL1
SCHEMBL17786300 0.70 SLC6A2 (0.41) L3MBTL1
SCHEMBL5510945 0.69 L3MBTL1 (0.42) L3MBTL1
SCHEMBL1612684 0.69 L3MBTL1 (0.39) L3MBTL1SIGMAR1CA12CA1CA9
SCHEMBL18096896 0.69 L3MBTL1 (0.34) L3MBTL1SIGMAR1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3911643-A1 ANTIMICROBIAL COMPOUNDS AND METHODS Curza Global LLC (US) 2021-11-24 EP disclosed
WO-2020150372-A1 ANTIMICROBIAL COMPOUNDS AND METHODS CURZA GLOBAL, LLC (US) 2020-07-23 WO disclosed