SCHEMBL22236486

SCHEMBL22236486

C/N=C(\NC)NCCC[C@H](C)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 1/20 0.53
▸ BLM P54132 1/20 0.41
▸ LTA4H P09960 1/20 0.38
▸ GABRR1 P24046 2/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ ACE2 Q9BYF1 1/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ GAA P10253 1/20 0.35
▸ ITGB3 P05106 1/20 0.32
▸ ITGA2B P08514 1/20 0.32
▸ SCN5A Q14524 1/20 0.32
▸ SCN2A Q99250 1/20 0.32
▸ TBXAS1 P24557 2/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ OTC P00480 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15199764 0.85 BLM (0.40) KDM1ABLMLTA4HGABRR1CYP1A2
SCHEMBL18071127 0.82 KDM1A (0.51) KDM1ABLMCYP1A2MEN1KMT2A
SCHEMBL4407451 0.82 KDM1A (0.51) KDM1ABLMCYP1A2MEN1KMT2A
SCHEMBL13485480 0.82 KDM1A (0.51) KDM1ABLMCYP1A2MEN1KMT2A
SCHEMBL14842600 0.82 KDM1A (0.51) KDM1ABLMCYP1A2MEN1KMT2A
SCHEMBL21196892 0.82 KDM1A (0.51) KDM1AMEN1KMT2AGAASCN5A
SCHEMBL22509292 0.82 KDM1A (0.51) KDM1AMEN1KMT2AGAASCN5A
SCHEMBL21195165 0.82 KDM1A (0.51) KDM1ABLMCYP1A2MEN1KMT2A
SCHEMBL287988 0.82 KDM1A (0.51) KDM1ABLMCYP1A2MEN1KMT2A
SCHEMBL25983177 0.80 KDM1A (0.62) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10717787-B1 Antibodies to symmetrically dimethylated arginine analytes and use thereof ARK DIAGNOSTICS, INC. (US) 2020-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10717787-B1 Antibodies to symmetrically dimethylated arginine analytes and use thereof PRMT3, PRMT5, PRMT1 KDM1A 881/4885BLM 3996/4885LTA4H 2809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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