Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 6/20 | 0.45 |
| ▸ | STS | P08842 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22088746 | 0.95 | STS (0.48) | HSD17B1STSLMNAMAPTESR1 | |
| SCHEMBL22088747 | 0.95 | STS (0.48) | HSD17B1STSLMNAMAPTESR1 | |
| SCHEMBL22089279 | 0.95 | STS (0.48) | HSD17B1STSLMNAMAPTESR1 | |
| SCHEMBL22236698 | 0.95 | STS (0.48) | HSD17B1STSLMNAMAPTESR1 | |
| SCHEMBL22524226 | 0.93 | HSD17B1 (0.53) | HSD17B1STSLMNAMAPTESR1 | |
| SCHEMBL22236741 | 0.93 | HSD17B1 (0.53) | HSD17B1STSLMNAMAPTESR1 | |
| SCHEMBL22236742 | 0.90 | HRH3 (0.46) | HSD17B1STSLMNAMAPTESR1 | |
| SCHEMBL22524224 | 0.90 | STS (0.53) | HSD17B1STSLMNAMAPTESR1 | |
| SCHEMBL18661043 | 0.89 | LMNA (0.56) | HSD17B1LMNAMAPTESR1HSD17B10 | |
| SCHEMBL22236702 | 0.87 | STS (0.56) | HSD17B1STSLMNAMAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10717761-B2 | Therapeutically active steroidal derivatives | FORENDO PHARMA LTD (FI) | 2020-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717761-B2 | Therapeutically active steroidal derivatives | HSD17B11, NR5A1, CYP17A1 | HSD17B1 4/4885STS 36/4885LMNA 2414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.