Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984470 | 0.79 | RIPK2 (0.46) | RIPK2 | |
| SCHEMBL19947347 | 0.77 | RIPK2 (1.00) | RIPK2 | |
| SCHEMBL24921189 | 0.72 | CYP11B1 (0.52) | RIPK2 | |
| SCHEMBL19947421 | 0.72 | KDM4E (0.44) | RIPK2 | |
| SCHEMBL12482670 | 0.71 | MKNK1 (0.56) | — | |
| SCHEMBL17130495 | 0.71 | RIPK2 (0.60) | RIPK2 | |
| SCHEMBL19947300 | 0.71 | RIPK2 (1.00) | RIPK2 | |
| SCHEMBL31015304 | 0.70 | CYP11B1 (0.43) | RIPK2 | |
| SCHEMBL17809683 | 0.70 | LRRK2 (0.54) | RIPK2 | |
| SCHEMBL31014572 | 0.69 | RAB9A (0.46) | RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512837-B1 | PYRIDINE AND PYRAZINE COMPOUNDS AS INHIBITORS OF RIPK2 | BOEHRINGER INGELHEIM INT (DE) | 2020-07-22 | — | — | EP | disclosed |