Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | SFRP1 | Q8N474 | 4/20 | 0.41 |
| ▸ | WNT3 | P56703 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14353853 | 0.99 | HTR6 (0.44) | POLBALDH1A1SMN1; SMN2MAPTHTR6 | |
| SCHEMBL2223827 | 0.86 | HTR6 (0.41) | POLBALDH1A1SMN1; SMN2MAPTHTR6 | |
| SCHEMBL2223900 | 0.86 | MEN1 (0.47) | POLBALDH1A1HTR6SFRP1WNT3 | |
| Hydrochloric Acid SCHEMBL14354519 | 0.85 | MEN1 (0.46) | POLBALDH1A1HTR6SFRP1WNT3 | |
| SCHEMBL2223746 | 0.80 | HTR6 (0.40) | HTR6SFRP1WNT3SSTR4SSTR1 | |
| SCHEMBL2223822 | 0.79 | HTR6 (0.41) | POLBALDH1A1SMN1; SMN2MAPTHTR6 | |
| Hydrochloric Acid SCHEMBL14353856 | 0.79 | HTR6 (0.40) | HTR6SFRP1WNT3SSTR4SSTR1 | |
| SCHEMBL16986606 | 0.78 | GLA (0.36) | ALDH1A1SMN1; SMN2MAPTHTR6 | |
| Hydrochloric Acid SCHEMBL2224896 | 0.78 | GLA (0.35) | POLBALDH1A1SMN1; SMN2MAPTHTR6 | |
| SCHEMBL2228934 | 0.75 | HTR6 (0.38) | HTR6SFRP1WNT3SSTR4SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521714-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-11-14 | — | — | EP | claimed |
| WO-2011083487-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-07-14 | — | — | WO | claimed |
| EP-2521714-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011083487-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-07-14 | — | — | WO | disclosed |