Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | WNT3 | P56703 | 1/20 | 0.35 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14353856 | 0.99 | HTR6 (0.40) | HTR6SSTR4SSTR1WNT3SFRP1 | |
| SCHEMBL2228934 | 0.86 | HTR6 (0.38) | HTR6SSTR4SSTR1WNT3SFRP1 | |
| Hydrochloric Acid SCHEMBL14354520 | 0.85 | HTR6 (0.38) | HTR6SSTR4SSTR1NSD2 | |
| SCHEMBL2223738 | 0.80 | POLB (0.44) | HTR6SSTR4SSTR1WNT3SFRP1 | |
| Hydrochloric Acid SCHEMBL14353853 | 0.79 | HTR6 (0.44) | HTR6SSTR4SSTR1WNT3SFRP1 | |
| SCHEMBL14354397 | 0.79 | HTR6 (0.41) | HTR6SSTR4SSTR1NSD2 | |
| SCHEMBL2223900 | 0.75 | MEN1 (0.47) | HTR6SSTR4SSTR1WNT3SFRP1 | |
| Hydrochloric Acid SCHEMBL14354519 | 0.74 | MEN1 (0.46) | HTR6SSTR4SSTR1WNT3SFRP1 | |
| SCHEMBL1015179 | 0.72 | HTR6 (0.55) | HTR6 | |
| SCHEMBL2222879 | 0.71 | NSD2 (0.53) | HTR6NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521714-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011083487-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-07-14 | — | — | WO | disclosed |