Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CD74 | P04233 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632053 | 0.84 | MAPT (0.47) | MAPTCD74MIFKDM4ERECQL | |
| SCHEMBL6953895 | 0.82 | MAPT (0.44) | MAPTKDM4ERECQLALDH1A1SLC6A2 | |
| SCHEMBL22426192 | 0.80 | MAPT (0.46) | MAPTCD74MIFKDM4ERECQL | |
| SCHEMBL20061340 | 0.76 | TDP1 (0.43) | MAPTKDM4ERECQLALDH1A1KCNH2 | |
| SCHEMBL23780909 | 0.75 | ACHE (0.44) | MAPTCD74MIFKDM4EKCNH2 | |
| SCHEMBL17842469 | 0.74 | SLC6A3 (0.46) | MAPTKDM4EALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL31143671 | 0.74 | SLC6A3 (0.46) | MAPTKDM4EALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL31143772 | 0.74 | SLC6A3 (0.46) | MAPTKDM4EALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL23610045 | 0.74 | SLC6A3 (0.46) | MAPTKDM4EALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL30616701 | 0.74 | SLC6A3 (0.46) | MAPTKDM4EALDH1A1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312175-B1 | HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT | KOREA RES INST CHEMICAL TECH (KR) | 2020-07-22 | — | — | EP | disclosed |