Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22239247 | 0.97 | GRIN2B (0.47) | GRIN2BGRIN1 | |
| SCHEMBL22239248 | 0.81 | GRIN2B (0.48) | GRIN2BGRIN1 | |
| SCHEMBL26019872 | 0.80 | GRIN2B (0.64) | GRIN2BGRIN1 | |
| SCHEMBL20090988 | 0.80 | GRIN2B (0.64) | GRIN2BGRIN1 | |
| SCHEMBL17643312 | 0.80 | GRIN2B (0.64) | GRIN2BGRIN1 | |
| SCHEMBL24270774 | 0.79 | HRH3 (0.36) | GRIN2B | |
| SCHEMBL24270959 | 0.79 | MEN1 (0.56) | GRIN2BGRIN1 | |
| SCHEMBL22239239 | 0.78 | GRIN2B (0.49) | GRIN2BGRIN1 | |
| SCHEMBL24270872 | 0.75 | HTR7 (0.36) | — | |
| SCHEMBL24136406 | 0.74 | GRIN1 (0.78) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3683207-A1 | N-ALKYLARYL-5-OXYARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2B | Cadent Therapeutics, Inc. (US) | 2020-07-22 | — | — | EP | disclosed |