Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19714186 | 0.86 | CNR2 (0.35) | CNR2CNR1BTKIDO1KDM4E | |
| SCHEMBL17777059 | 0.86 | CNR2 (0.35) | CNR2CNR1BTKIDO1KDM4E | |
| SCHEMBL22239940 | 0.84 | GPR6 (0.35) | KDM4EALDH1A1ACACBNOS2 | |
| SCHEMBL22240211 | 0.82 | ADORA2B (0.34) | CNR2 | |
| SCHEMBL22240125 | 0.81 | BTK (0.33) | CNR2CNR1BTKNOS2 | |
| SCHEMBL22239553 | 0.78 | CNR2 (0.35) | CNR2CNR1BTK | |
| SCHEMBL20733153 | 0.77 | GRM5 (0.36) | BTK | |
| SCHEMBL22239897 | 0.77 | JAK2 (0.36) | CNR2KDM4EALDH1A1HPGDNOS2 | |
| SCHEMBL17777106 | 0.77 | NPC1 (0.37) | CNR2CNR1KDM4E | |
| SCHEMBL16754306 | 0.77 | NPC1 (0.37) | CNR2CNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221317-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-07-22 | — | — | EP | disclosed |