Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754368 | 0.79 | F2 (0.49) | F2F12GAAMAPTALDH1A1 | |
| SCHEMBL896911 | 0.74 | GAA (0.60) | F2F12FAAHGAAMAPT | |
| SCHEMBL15890202 | 0.73 | NPC1 (0.54) | F2F12GAAMAPTALDH1A1 | |
| SCHEMBL821809 | 0.72 | F2 (0.52) | F2F12GAAMAPTALDH1A1 | |
| SCHEMBL1780143 | 0.70 | TAS2R14 (0.54) | F2F12GAAPKM | |
| SCHEMBL17775078 | 0.69 | MAPK14 (0.38) | F2F12MAPTALDH1A1MAPKAPK2 | |
| SCHEMBL18654581 | 0.69 | KDM4E (0.43) | KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL7244914 | 0.68 | ALDH1A1 (0.56) | F2F12GAAMAPTALDH1A1 | |
| SCHEMBL1576702 | 0.67 | MAPT (0.59) | F2F12GAAMAPTALDH1A1 | |
| SCHEMBL18654720 | 0.66 | KDM4C (0.43) | MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221317-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-07-22 | — | — | EP | disclosed |