SCHEMBL22240643

SCHEMBL22240643

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)oc3cc(-c5cccc6sc7ccccc7c56)ccc34)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 1/20 0.38
BRDT Q58F21 1/20 0.36
LIMK1 P53667 1/20 0.36
ALOX5 P09917 2/20 0.35
F9 P00740 1/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPT P10636 3/20 0.35
HPGD P15428 3/20 0.35
KDM4E B2RXH2 2/20 0.35
ATM Q13315 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
MAPK1 P28482 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22760460 0.99 PRKDC (0.37) PRKDCBRDTLIMK1ALOX5F9
SCHEMBL22760329 0.98 PRKDC (0.37) PRKDCBRDTLIMK1ALOX5F9
SCHEMBL25458878 0.96 PRKDC (0.36) PRKDCBRDTLIMK1ALOX5F9
SCHEMBL24097528 0.96 PRKDC (0.36) PRKDCBRDTLIMK1ALOX5F9
SCHEMBL22240851 0.95 PRKDC (0.36) PRKDCBRDTLIMK1ALOX5F9
SCHEMBL24216811 0.95 PRKDC (0.36) PRKDCBRDTLIMK1ALOX5F9
SCHEMBL25645666 0.95 HCRTR1 (0.37) PRKDCBRDTLIMK1ALOX5F9
SCHEMBL25645642 0.95 PRKDC (0.36) PRKDCBRDTLIMK1ALOX5F9
SCHEMBL25646009 0.95 F9 (0.36) PRKDCBRDTLIMK1ALOX5F9
SCHEMBL26192848 0.95 BRDT (0.37) PRKDCBRDTLIMK1ALOX5F9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257586-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-10-11 EP disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
US-11515484-B2 Heterocyclic compound and organic light emitting element comprising same LT MATERIALS CO., LTD. (KR) 2022-11-29 US disclosed
WO-2022025714-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2022-02-03 WO disclosed
WO-2022015084-A1 ORGANIC LIGHT-EMITTING ELEMENT 주식회사 엘지화학 2022-01-20 WO disclosed
US-20200266355-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME HEESUNG MATERIAL LTD. (KR) 2020-08-20 US disclosed
EP-3683217-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT Materials Co., Ltd. (KR) 2020-07-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11515484-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, CYP1A1 PRKDC 4595/4885BRDT 1960/4885LIMK1 547/4885
US-20200266355-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 PRKDC 4595/4885BRDT 1960/4885LIMK1 547/4885
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CYP1A2, CYP1A1 PRKDC 3767/4885BRDT 3698/4885LIMK1 674/4885
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 PRKDC 3471/4885BRDT 3513/4885LIMK1 201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.