SCHEMBL22240902

SCHEMBL22240902

OB(O)c1cccc(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.53
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TSPO P30536 5/20 0.41
PLG P00747 1/20 0.36
F12 P00748 1/20 0.36
F11 P03951 1/20 0.36
KLKB1 P03952 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
KMT2A Q03164 1/20 0.36
HDAC4 P56524 1/20 0.36
DNM1 Q05193 1/20 0.35
COMT P21964 1/20 0.35
PTGER4 P35408 1/20 0.34
ENPP2 Q13822 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15034697 0.96 KDM4E (0.50) MGLLKDM4EATML3MBTL1CA1
SCHEMBL29410814 0.96 KDM4E (0.50) MGLLKDM4EATML3MBTL1CA1
SCHEMBL29410817 0.96 KDM4E (0.50) MGLLKDM4EATML3MBTL1CA1
SCHEMBL2402143 0.96 MGLL (0.57) MGLLKDM4EATML3MBTL1CA1
SCHEMBL12415360 0.93 MGLL (0.54) MGLLKDM4EATML3MBTL1CA1
SCHEMBL29634627 0.93 MGLL (0.54) MGLLKDM4EATML3MBTL1CA1
SCHEMBL12415352 0.92 MGLL (0.49) MGLLKDM4EATML3MBTL1CA1
SCHEMBL13039494 0.92 MGLL (0.53) MGLLKDM4EATML3MBTL1CA1
SCHEMBL29669667 0.90 MGLL (0.50) MGLLKDM4EATML3MBTL1CA1
SCHEMBL14148357 0.90 MGLL (0.50) MGLLKDM4EATML3MBTL1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3683217-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT Materials Co., Ltd. (KR) 2020-07-22 EP disclosed