SCHEMBL2402143

SCHEMBL2402143

OB(O)c1cccc(-n2c3ccc(-c4ccccc4)cc3c3cc(-c4ccccc4)ccc32)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.57
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
PLG P00747 1/20 0.39
F12 P00748 1/20 0.39
F11 P03951 1/20 0.39
KLKB1 P03952 1/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
COMT P21964 1/20 0.37
ENPP2 Q13822 4/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
KDM4E B2RXH2 2/20 0.37
ATM Q13315 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22240902 0.96 MGLL (0.53) MGLLCA1CA2PLGF12
SCHEMBL23814165 0.93 MGLL (0.51) MGLLCA1CA2PLGF12
SCHEMBL29410817 0.92 KDM4E (0.50) MGLLCA1CA2PLGF12
SCHEMBL29410814 0.92 KDM4E (0.50) MGLLCA1CA2PLGF12
SCHEMBL15034697 0.92 KDM4E (0.50) MGLLCA1CA2PLGF12
SCHEMBL322024 0.90 MGLL (0.50) MGLLCA1CA2COMTENPP2
SCHEMBL12415360 0.89 MGLL (0.54) MGLLCA1CA2PLGF12
SCHEMBL29634627 0.89 MGLL (0.54) MGLLCA1CA2PLGF12
SCHEMBL12415357 0.88 MGLL (0.56) MGLLCA1CA2COMTENPP2
SCHEMBL29419984 0.88 MGLL (0.56) MGLLCA1CA2COMTENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108727389-B Pyrene derivative and application thereof in organic luminescent material 北京鼎材科技有限公司 2020-09-18 CN disclosed
CN-106083835-B Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2020-01-07 CN disclosed
US-10224490-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-05 US disclosed
US-20180130958-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130958-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-10 US disclosed
US-9899608-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-20 US disclosed
US-9899608-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-20 US disclosed
EP-2363398-B1 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2017-10-18 EP disclosed
US-20150318493-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, And Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-05 US disclosed
US-20150318493-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, And Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-05 US disclosed
US-20150318493-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, And Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-05 US disclosed
US-9079879-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-14 US disclosed
US-9079879-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-14 US disclosed
US-9079879-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-14 US disclosed
EP-2363398-A1 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-09-07 EP disclosed
US-20110210316-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-09-01 US disclosed
US-20110210316-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-09-01 US disclosed
US-20110210316-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110210316-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NQO1, DDT, CYP1A1 MGLL 3263/4885CA1 3369/4885CA2 3225/4885
US-20180130958-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NQO1, DDT, CYP1A1 MGLL 3263/4885CA1 3369/4885CA2 3225/4885
US-10224490-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device NQO1, DDT, CYP1A1 MGLL 3263/4885CA1 3369/4885CA2 3225/4885
US-20150318493-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, And Lighting Device NQO1, DDT, CYP1A1 MGLL 3263/4885CA1 3369/4885CA2 3225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.