Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220307 | 0.80 | CYP1A2 (0.51) | CPA1ALDH1A1CYP1A2TSHRHTT | |
| SCHEMBL220308 | 0.80 | CYP1A2 (0.51) | CPA1ALDH1A1CYP1A2TSHRHTT | |
| SCHEMBL2760491 | 0.79 | MDM2 (0.33) | TSHRMDM2HTTCES2CES1 | |
| SCHEMBL221352 | 0.79 | TDP1 (0.47) | CPA1ALDH1A1CYP3A4MDM2HTT | |
| SCHEMBL221353 | 0.79 | TDP1 (0.47) | CPA1ALDH1A1CYP3A4MDM2HTT | |
| SCHEMBL222290 | 0.78 | NPSR1 (0.48) | CPA1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL220493 | 0.78 | CTNNB1 (0.45) | CPA1ALDH1A1CYP3A4CYP1A2HTT | |
| SCHEMBL222291 | 0.78 | NPSR1 (0.48) | CPA1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL220492 | 0.78 | CTNNB1 (0.45) | CPA1ALDH1A1CYP3A4CYP1A2HTT | |
| SCHEMBL6249908 | 0.74 | CPA1 (0.46) | CPA1ALDH1A1CYP3A4MDM2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940938-B2 | Michael reaction with recovery of the catalyst | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-27 | — | — | US | disclosed |
| US-8940938-B2 | Michael reaction with recovery of the catalyst | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-27 | — | — | US | disclosed |
| US-8940938-B2 | Michael reaction with recovery of the catalyst | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-27 | — | — | US | disclosed |
| US-20120004424-A1 | MICHAEL REACTION WITH RECOVERY OF THE CATALYST | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-05 | — | — | US | disclosed |
| US-20120004424-A1 | MICHAEL REACTION WITH RECOVERY OF THE CATALYST | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004424-A1 | MICHAEL REACTION WITH RECOVERY OF THE CATALYST | CYP2E1, CYP11B2, CYP11B1 | CPA1 3043/4885ALDH1A1 118/4885CYP3A4 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.