Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222291 | 1.00 | NPSR1 (0.48) | NPSR1HTTPOLBL3MBTL1MAPT | |
| SCHEMBL22831440 | 0.88 | NPSR1 (0.50) | NPSR1HTTPOLBL3MBTL1MAPT | |
| SCHEMBL4126682 | 0.85 | ALDH1A1 (0.49) | NPSR1HTTPOLBL3MBTL1MAPT | |
| SCHEMBL29434462 | 0.84 | ALDH1A1 (0.64) | NPSR1HTTPOLBL3MBTL1MAPT | |
| SCHEMBL18106486 | 0.84 | ALDH1A1 (0.64) | NPSR1HTTPOLBL3MBTL1MAPT | |
| SCHEMBL16785486 | 0.84 | ALDH1A1 (0.64) | NPSR1HTTPOLBL3MBTL1MAPT | |
| SCHEMBL29896531 | 0.82 | ALDH1A1 (0.52) | NPSR1HTTPOLBL3MBTL1MAPT | |
| SCHEMBL219605 | 0.82 | L3MBTL1 (0.50) | NPSR1HTTPOLBL3MBTL1MAPT | |
| SCHEMBL219604 | 0.82 | L3MBTL1 (0.50) | NPSR1HTTPOLBL3MBTL1MAPT | |
| SCHEMBL220308 | 0.81 | CYP1A2 (0.51) | HTTPOLBL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940938-B2 | Michael reaction with recovery of the catalyst | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-27 | — | — | US | disclosed |
| US-8940938-B2 | Michael reaction with recovery of the catalyst | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-27 | — | — | US | disclosed |
| US-8940938-B2 | Michael reaction with recovery of the catalyst | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-27 | — | — | US | disclosed |
| US-20120004424-A1 | MICHAEL REACTION WITH RECOVERY OF THE CATALYST | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-05 | — | — | US | disclosed |
| US-20120004424-A1 | MICHAEL REACTION WITH RECOVERY OF THE CATALYST | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004424-A1 | MICHAEL REACTION WITH RECOVERY OF THE CATALYST | CYP2E1, CYP11B2, CYP11B1 | NPSR1 1848/4885HTT 2660/4885POLB 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.