Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 11/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15571317 | 0.90 | AKR1C3 (0.52) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL15572316 | 0.85 | AKR1C3 (0.58) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL2219869 | 0.85 | AKR1C3 (0.57) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL2222865 | 0.84 | AKR1C3 (0.47) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL8796288 | 0.79 | AKR1C3 (0.48) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL8603397 | 0.76 | AKR1C3 (0.47) | AKR1C3PTGS2 | |
| SCHEMBL8521003 | 0.76 | PTGS2 (0.45) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL8430221 | 0.74 | AKR1C3 (0.45) | AKR1C3 | |
| SCHEMBL15572432 | 0.74 | PTGS2 (0.34) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL5138929 | 0.74 | AKR1C3 (0.43) | AKR1C3PTGS2AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088474-A2 | SULINDAC AND SULINDAC DERIVATIVES AND THEIR USES RELATED TO INFECTION | Zirus, Inc. (US) | 2011-07-21 | — | — | WO | disclosed |