SCHEMBL2224314

SCHEMBL2224314

Cc1c([N+](=O)[O-])cc([N+](=O)[O-])c(O)c1[N+](=O)[O-]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 9/20 0.59
ALDH1A1 P00352 3/20 0.52
TDP1 Q9NUW8 3/20 0.47
TSHR P16473 1/20 0.47
CYP1A2 P05177 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
TTR P02766 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
MAPK1 P28482 1/20 0.46
RECQL P46063 1/20 0.46
PMP22 Q01453 1/20 0.46
KMT2A Q03164 1/20 0.46
HIF1A Q16665 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CRHBP P24387 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30785537 1.00 GPR35 (0.59) GPR35ALDH1A1TDP1TSHRCYP1A2
SCHEMBL28650556 0.86 GPR35 (0.55) GPR35ALDH1A1TDP1TSHRCYP1A2
SCHEMBL30692367 0.86 GPR35 (0.57) GPR35ALDH1A1TDP1TSHRCYP1A2
SCHEMBL29457573 0.86 GPR35 (0.57) GPR35ALDH1A1TDP1CYP1A2KDM4E
SCHEMBL28728496 0.86 GPR35 (0.57) GPR35ALDH1A1TDP1CYP1A2KDM4E
SCHEMBL21143325 0.86 GPR35 (0.52) GPR35ALDH1A1TDP1TSHRCYP1A2
SCHEMBL7788794 0.86 GPR35 (0.57) GPR35ALDH1A1TDP1TSHRCYP1A2
Methyl Alcohol SCHEMBL29086960 0.85 GPR35 (0.59) GPR35ALDH1A1TDP1CYP1A2KDM4E
SCHEMBL2519558 0.85 TSHR (0.55) GPR35ALDH1A1TDP1TSHRCYP1A2
SCHEMBL69964 0.85 GPR35 (0.59) GPR35ALDH1A1TDP1CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516355-B1 FUSIBLE/CASTABLE EXPLOSIVE COMPOSITION HAVING LOW VULNERABILITY NEXTER MUNITIONS (FR) 2017-08-23 EP claimed
US-9242906-B2 Melt-cast insensitive explosive composition NEXTER MUNITIONS (FR) 2016-01-26 US claimed
US-20120305149-A1 MELT-CAST INSENSITIVE EXPLOSIVE COMPOSITION NEXTER MUNITIONS (FR) 2012-12-06 US claimed
EP-0814069-B1 Meltable/castable explosive composition with reduced sensitivity GIAT IND SA (FR) 2002-03-27 EP claimed
EP-0814069-A1 Meltable/castable explosive composition with reduced sensitivity GIAT INDUSTRIES (FR) 1997-12-29 EP claimed
WO-1995020637-A2 HYDROCARBON OIL-AQUEOUS FUEL AND ADDITIVE COMPOSITIONS MEG S.N.C. DI SCOPELLITI SOFIA & C. (IT) 1995-08-03 WO claimed
CN-114133340-B Oxalyl dihydrazide nitrate metal complex suitable for solid propellant and preparation method thereof 湖北航天化学技术研究所 2024-03-15 CN disclosed
CN-114133340-A Oxalyl dihydrazide nitrate metal complex suitable for solid propellant and preparation method thereof 湖北航天化学技术研究所 2022-03-04 CN disclosed
US-20210048389-A1 METHOD FOR THE DETECTION OF ANALYTES VIA LUMINESCENCE QUENCHING UNIV QUEENSLAND (AU) 2021-02-18 US disclosed
EP-2929325-B1 METHOD FOR THE DETECTION OF ANALYTES VIA LUMINESCENCE QUENCHING UNIV QUEENSLAND (AU) 2020-06-24 EP disclosed
CN-104956206-B Method for detecting analytes via luminescence quenching 昆士兰大学 2020-05-05 CN disclosed
EP-2318331-B1 PROCESS FOR TASKING AN EXPLOSIVE MATERIAL OF REDUCED VULNERABILITY AND MATERIAL EMPLOYED IN SUCH A PROCESS NEXTER MUNITIONS (FR) 2020-04-08 EP disclosed
CN-106463192-B Photovoltaic power generation system and correlation technique 辉光能源公司 2019-05-21 CN disclosed
EP-0953546-A2 Method for decomposing nitroaromatic compounds in waste waters BASF AKTIENGESELLSCHAFT (DE) 1999-11-03 EP disclosed
EP-0814069-A1 Meltable/castable explosive composition with reduced sensitivity GIAT INDUSTRIES (FR) 1997-12-29 EP disclosed
WO-1995020637-A2 HYDROCARBON OIL-AQUEOUS FUEL AND ADDITIVE COMPOSITIONS MEG S.N.C. DI SCOPELLITI SOFIA & C. (IT) 1995-08-03 WO disclosed
EP-0256504-B1 PROCESS FOR THE EXTRACTION OF NITRO-HYDROXY-AROMATES FROM AQUEOUS SOLUTIONS HOECHST AKTIENGESELLSCHAFT (DE) 1990-12-27 EP disclosed
US-4814518-A SOLVENT EXTRACTION, AMINE SALTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-21 US disclosed
EP-0256504-A1 Process for the extraction of nitro-hydroxy-aromates from aqueous solutions HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-24 EP disclosed
US-3984405-A PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES E. R. SQUIBB & SONS, INC. (US) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210048389-A1 METHOD FOR THE DETECTION OF ANALYTES VIA LUMINESCENCE QUENCHING TYR, MAOA, AS3MT GPR35 3630/4885ALDH1A1 1114/4885TDP1 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.